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oaioai:ir.cc.sapmed.ac.jp:123456789/7180

The Antigen ASB4 on Cancer Stem Cells Serves as a Target for CTL Immunotherapy of Colorectal Cancer

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    Publication date
    2018
    Publisher
    札幌医科大学

    Abstract

    網羅的なHLAリガンドーム解析により，がん幹細胞（cancer stem cell，CSC）に特異的なASB4由来のペプチドIV9を同定し，CSCを特異的に傷害可能なCTL免疫療法となることを示した．更にCSCを標的としたCTL免疫療法が再発予防として有用であることを明らかにした

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