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原著

By 照義 野口 and TERUYOSHI NOGUCHI

Abstract

Renal autotransplantation in adult mongrel dogs were performed to study the surgical technique of renal transplantation. These animals were divided into 2 groups, 1) Group I: the renal artery and vein were anastomosed to the right external iliac artery and common iliac vein respectively with end-to-end anastomosis. The distal tip of the ureter was implanted into the urinary bladder through a stab wound. The kidney was placed in the hollow of the lateral peritoneal surface, and fixed with a suture through the pericapsular tissue and peritoneal wall. 2) Group II : the renal artery was anastomosed to the right external artery with end-to-end anastomosis. The renal vein was anastomosed to the inferior vena cava at the approximately 2 centimeters cranial to the bifurcation with side-to-end anastomosis. The distal tip of the ureter was implanted into the urinary bladder through a stab wound. The kidney was placed into the hollow of the lateral retroperitoneal space and fixed with peritoneal covering. The group II was more excellent than group I in the points of long term survival, renal blood flow, renal blood outflow, development of the thrombosis at the anastomosis, and convenience of renal fixation. Then renal homotransplantation was performed with the surgical technique of group II. The average survival period of 5 dogs without immunosuppressive drugs was 5.4 days with range of 4 to 7 days. This period was a little longer than bilateral nephrectomized dogs which survived from 3 to 6 days after nephrectomy. The average survival period of 5 dogs with Imuran and Dexamethasone was 18.7 days with range of 12 to 25 days and all of these died from renal failure or rejection, sepsis, and side effects of drugs

Publisher: 千葉医学会
Year: 1968
OAI identifier: oai:opac.ll.chiba-u.jp:900114509
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