research article
oaioai:doaj.org/article:9d33b3d437694a269bf14279477e36ac

New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infection: report of a survivor

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Publication date
1 February 2016
Publisher
'FapUNIFESP (SciELO)'
Doi

    Abstract

    Abstract: New Delhi metallo-beta-lactamase-1 (NDM-1) is a bacterial enzyme that renders the bacteria resistant to a variety of beta-lactam antibiotics. A 20-year-old man was hospitalized several times for surgical treatment and complications caused by a right-sided vestibular schwannoma. Although the patient acquired several multidrug-resistant infections, this study focuses on the NDM-1-producing Acinetobacter spp. infection. As it was resistant to all antimicrobials tested, the medical team developed a 20-day regimen of 750mg/day metronidazole, 2,000,000IU/day polymyxin B, and 100mg/day tigecycline. The treatment was effective, and the patient recovered and was discharged from the hospital

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