Skip to main content
Article thumbnail
Location of Repository

Synthesis and Biological Activities of Novel (3-Methylquinoxalin-2-YL)Hydrazones and Osazones of Aldoses

By Gamal A. El-Hiti, Safa Mahgoub, Mohamed F. Abdel-Megeed and Yehia A.-G. Mahmoud

Abstract

Condensation of equimolar amounts of 2-hydrazino-3-\ud methylquinoxaline (I) and monosaccharides II (D-glucose, Dgalactose, D-xylose, D-arabinose and D-ribose) in boiling ethanol in the presence of glacial acetic acid afforded the corresponding hydrazones III in good yields. However, when the reaction was conducted with three molar equivalents of I the corresponding osazones V was obtained in fair yields. Acetylation of the hydrazones III and osazones V using acetic anhydride in the presence of pyridine at room temperature gave the corresponding acetyl derivatives IV and VI, respectively in excellent yields. The antimicrobial activities of the synthesised compounds were examined against a variety of tested organisms. Some of the\ud synthesised compounds showed antimicrobial activities

Topics: QD
Publisher: Faculty of Science, University of Tanta
Year: 1999
OAI identifier: oai:http://orca.cf.ac.uk:16378
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.