Skip to main content
Article thumbnail
Location of Repository

An Adaptable, Portable Microarray Reader for Biodetection

By Deanna L. Thompson, Francesca Pearson, Cynthia Thomas, Rupa Rao, Dennis Matthews, Joanna S. Albala, Sebastian Wachsmann-Hogiu and Matthew A. Coleman


We have developed an inexpensive portable microarray reader that can be applied to standard microscope slide-based arrays and other array formats printed on chemically modified surfaces. Measuring only 19 cm in length, the imaging device is portable and may be applicable to both triage and clinical settings. For multiplexing and adaptability purposes, it can be modified to work with multiple excitation/emission wavelengths. Our device is shown to be comparable to a commercial laser scanner when detecting both streptavidin-biotin and antibody interactions. This paper presents the development and characterization of a handheld microarray imager and directly compares it with a commercial scanner

Topics: Article
Publisher: Molecular Diversity Preservation International (MDPI)
OAI identifier:
Provided by: PubMed Central

Suggested articles


  1. (2000). A microarray enzyme-linked immunosorbent assay for autoimmune diagnostics. Electrophoresis
  2. (1989). A rapid and sensitive method for the identification of Leishmania with monoclonal antibodies using fluorescein-labelled avidin.
  3. A rapid multiplexed diagnostic system for breast cancer.
  4. (2001). Advances in protein microarray technology for protein expression and interaction profiling.
  5. (2005). Antibody Arrays in Cancer Research.
  6. (2004). Comparison of multiplexed techniques for detection of bacterial and viral
  7. (2007). Development of a first-responder fluorescence reader for microarray cytokine assay of human immune response to disease.
  8. (1999). DNA biochip using a phototransistor integrated circuit.
  9. (1984). Enzyme-immunoassay: a review.
  10. (2002). Fully automatic quantification of microarray image data. Genome Res.
  11. (1999). Highthroughput microarray-based enzyme-linked immunosorbent assay (ELISA). Biotechniques
  12. (2002). Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment.
  13. (2001). Portable system for microbial sample preparation and oligonucleotide microarray analysis.
  14. (2000). Printing Proteins as Microarrays for High-Throughput Function Determination. Science
  15. (2001). Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions. Genome Biol.
  16. (2002). Rapid and sensitive determination of epinephrine and norepinephrine in urine and plasma by non-competitive enzyme immunoassay,

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.