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Lichen Striatus Occurring after Allogenic Peripheral Blood Stem Cell Transplantation in an Adult with Aplastic Anemia

By Je-Ho Mun, Hyun-Je Park, Hoon-Soo Kim, Su-Han Kim, Hyun-Chang Ko, Byung-Soo Kim and Moon-Bum Kim

Abstract

Lichens striatus (LS) is an acquired, self-limiting inflammatory dermatosis that follows the lines of Blaschko. The etiology of the eruption is unknown, but several theories have been proposed with focus on environmental factors, viral infection, cutaneous injury, hypersensitivity, and genetic predisposition. We describe a 19-year-old woman who developed a unilateral linear eruption 17 months after allogenic peripheral blood stem cell transplantation. Histopathology revealed features, which were consistent with LS. To the best of our knowledge, our patient is the first case describing the appearance of LS occurring after allogenic stem cell transplantation. We speculate that this condition represents an unusual form of localized, chronic graft-versus-host disease

Topics: Case Report
Publisher: Korean Dermatological Association; The Korean Society for Investigative Dermatology
OAI identifier: oai:pubmedcentral.nih.gov:3283860
Provided by: PubMed Central
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    1. Cutaneous graft versus host disease.
    2. Cutaneous graft-versus-host disease: a guide for the dermatologist.
    3. Genetic mosaicism in an acquired inflammatory dermatosis following the lines of Blaschko.
    4. Lichen striatus: clinical and laboratory features of 115 children.
    5. Unilateral linear lichenoid eruption after bone marrow transplantation: an unmasking of tolerance to an abnormal keratinocyte clone?

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