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Alterations in the transcriptome and antibiotic susceptibility of Staphylococcus aureus grown in the presence of diclofenac

By James T Riordan, JoAnne M Dupre, Stephanie A Cantore-Matyi, Atul Kumar-Singh, Yang Song, Shahrear Zaman, Sonia Horan, Nada S Helal, Vijayaraj Nagarajan, Mohamed O Elasri, Brian J Wilkinson and John E Gustafson
Topics: Research
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:3158543
Provided by: PubMed Central

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  1. (2000). A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother
  2. (2001). A new mathematical model for relative quantification in realtime RT-PCR.
  3. (2005). A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline. Antimicrob Agents Chemother
  4. (1995). A: EmrR is a negative regulator of the Escherichia coli multidrug resistance pump EmrAB.
  5. (1999). Acetylsalicylic acid reduces vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus endocarditis through antiplatelet and antibacterial effects. Circulation
  6. (2003). al: Impact of sigB mutation on Staphylococcus aureus oxacillin and vancomycin resistance varies with parental background and method of assessment.
  7. (2007). al: Potential management of resistant microbial infections with a novel non-antibiotic: the anti-inflammatory drug diclofenac sodium.
  8. (1993). al: Salicylate induction of antibiotic resistance in Escherichia coli: activation of the mar operon and a mar-independent pathway.
  9. (2002). al: sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J Bacteriol
  10. (2007). Aspirin treatment is associated with a significantly decreased risk of Staphylococcus aureus bacteremia in hemodialysis patients with tunneled catheters.
  11. (1975). Capsular antibodies induce type-specific phagocytosis of capsulated Staphylococcus aureus by human polymorphonuclear leukocytes. Infect Immun 1988, 56(5):1090-5. Riordan et al.
  12. (1990). Correlation of quinolone MIC and inhibition of DNA, RNA, and protein synthesis and induction of the SOS response in Escherichia coli. Antimicrob Agents Chemother
  13. (1984). Defais M: Signal of induction of recA protein
  14. (2001). Demple B: Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate.
  15. (2007). Elasri MO: SAMMD: Staphylococcus aureus microarray metadatabase.
  16. (1992). Emr, an Escherichia coli locus for multidrug resistance. Proc Natl Acad Sci USA
  17. (2007). et al: Activity of diclofenac used alone and in combination with streptomycin against Mycobacterium tuberculosis in mice.
  18. (2007). et al: Anaerobic gene expression in Staphylococcus aureus.
  19. (1998). et al: Antibacterial activity of the antiinflammatory agent diclofenac sodium.
  20. (1986). et al: Autoregulation of the nar operon encoding nitrate reductase in Escherichia coli. Mol Gen Genet
  21. (1994). et al: Bacterial resistance to uncouplers.
  22. (2005). et al: Characterization of Staphylococcus aureus mutants expressing reduced susceptibility to common house-cleaners.
  23. (2004). et al: Characterization of virulence factor regulation by SrrAB, a two-component system in Staphylococcus aureus.
  24. (1986). et al: Conversion of a homogeneously methicillin-resistant strain of Staphylococcus aureus to heterogeneous resistance by Tn551-mediated insertional inactivation.
  25. (2004). et al: Cytokine release does not improve the sensitivity and specificity of the direct popliteal lymph node assay. Toxicology
  26. (2004). et al: Effect of sodium diclofenac on serum and tissue concentration of amoxicillin and on staphylococcal infection. Biol Pharm Bull
  27. (2004). et al: Effects of sarA inactivation on the intrinsic multidrug resistance mechanism of Staphylococcus aureus.
  28. (1988). et al: Enhancement of the therapeutic effect of cephalosporins in experimental endocarditis by altering their pharmacokinetics with diclofenac. J Pharmacol Exp Ther
  29. (2003). et al: Evaluation of a synergistic combination between the non-antibiotic microbicides diclofenac and trifluoperazine.
  30. (2002). et al: Experimental studies on synergism between aminoglycosides and the antimicrobial antiinflammatory agent diclofenac sodium.
  31. (1998). et al: Identification of a gene essential for O-acetylation of the Staphylococcus aureus type 5 capsular polysaccharide. Mol Microbiol
  32. (1999). et al: Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides.
  33. (2006). et al: Influence of the two-component system SaeRS on global gene expression in two different Staphylococcus aureus strains.
  34. (1998). et al: Mechanism of salicylate-mediated inhibition of biofilm in Staphylococcus epidermidis.
  35. (1997). et al: Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility.
  36. (2003). et al: Molecular architecture of the regulatory Locus sae of Staphylococcus aureus and its impact on expression of virulence factors.
  37. (2007). et al: Response of Staphylococcus aureus to salicylate challenge.
  38. (2006). et al: Salicylic acid activates sigma factor B by rsbU-dependent and -independent mechanisms.
  39. (1995). et al: Separate mechanisms activate sigma B of Bacillus subtilis in response to environmental and metabolic stresses.
  40. (2001). et al: Structural mechanisms of QacR induction and multidrug recognition. Science
  41. (2000). et al: The anti-bacterial action of diclofenac shown by inhibition of DNA synthesis.
  42. (2009). et al: The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target.
  43. (2008). et al: The fusidic acid stimulon of Staphylococcus aureus.
  44. (2006). et al: The sigmaB regulon in Staphylococcus aureus and its regulation.
  45. (1999). et al: The Staphylococcus aureus rsbW (orf159) gene encodes an anti-sigma factor of SigB.
  46. (2005). et al: The TetR family of transcriptional repressors. Microbiol Mol Biol Rev
  47. (2003). et al: Transcriptional induction of the penicillin-binding protein 2 gene in Staphylococcus aureus by cell wall-active antibiotics oxacillin and vancomycin. Antimicrob Agents Chemother
  48. (2005). Gene expression profiling analysis of Mycobacterium tuberculosis genes in response to salicylate. Arch Microbiol
  49. (1999). Growth in the presence of salicylate increases fluoroquinolone resistance in Staphylococcus aureus. Antimicrob Agents Chemother
  50. (2001). Gustafson JE: Increases in the mutation frequency at which fusidic acid-resistant Staphylococcus aureus arise with salicylate.
  51. Hooper DC: Phosphorylation of MgrA and its effect on expression of the NorA and NorB efflux pumps of Staphylococcus aureus.
  52. (2005). HP Schweizer: Bacterial resistance to antibiotics: active efflux and reduced uptake. Adv Drug Deliv Rev
  53. (2004). JC: Staphylococcus aureus capsular polysaccharides. Clin Microbiol Rev
  54. (2006). JE: Contributions of sigB and sarA to distinct multiple antimicrobial resistance mechanisms of Staphylococcus aureus.
  55. (2000). JE: The effects of salicylate on bacteria.
  56. (2002). JE: The multidrug efflux pump NorA is not required for salicylate-induced reduction in drug accumulation by Staphylococcus aureus.
  57. (2009). JH: In vitro synergistic effect of gentamicin with the anti-inflammatory agent diclofenac against Listeria monocytogenes. Lett Appl Microbiol
  58. (1992). Mapping and characterization of multiple chromosomal factors involved in methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother
  59. (2005). Molecular analysis and organization of the sigmaB operon in Staphylococcus aureus.
  60. (1988). Nitrate respiration in relation to facultative metabolism in enterobacteria. Microbiol Rev
  61. (1985). Nonheritable resistance to chloramphenicol and other antibiotics induced by salicylates and other chemotactic repellents
  62. (1991). Piddock LJ: A comparison of methods used for measuring the accumulation of quinolones by Enterobacteriaceae, Pseudomonas aeruginosa and Staphylococcus aureus.
  63. (2002). Pine oil cleaner-resistant Staphylococcus aureus: reduced susceptibility to vancomycin and oxacillin and involvement of SigB. Appl Environ Microbiol
  64. (1999). Pinho MG, Tomasz A: Inactivated pbp4 in highly glycopeptide-resistant laboratory mutants of Staphylococcus aureus.
  65. (2003). Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus.
  66. (1983). SB: Amplifiable resistance to tetracycline, chloramphenicol, and other antibiotics in Escherichia coli: involvement of a non-plasmid-determined efflux of tetracycline.
  67. (1988). SB: marA locus causes decreased expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli.
  68. (1996). SB: Multiple antibiotic resistance (mar) locus protects Escherichia coli from rapid cell killing by fluoroquinolones. Antimicrob Agents Chemother
  69. (2001). Schlievert PM: Identification of a novel twocomponent regulatory system that acts in global regulation of virulence factors of Staphylococcus aureus.
  70. (2006). Seo SM: MepR, a repressor of the Staphylococcus aureus MATE family multidrug efflux pump MepA, is a substrateresponsive regulatory protein. Antimicrob Agents Chemother
  71. (2005). Seo SM: Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein. Antimicrob Agents Chemother
  72. (2001). Sigma(B) activity depends on RsbU in Staphylococcus aureus.
  73. (2001). Significance analysis of microarrays applied to the ionizing radiation response.
  74. (1987). Skurray R: Antimicrobial resistance of Staphylococcus aureus: genetic basis. Microbiol Rev
  75. (2001). Skurray RA: Staphylococcal multidrug efflux protein QacA.
  76. (1995). Staphylococcus aureus penicillin-binding protein 4 and intrinsic beta-lactam resistance. Antimicrob Agents Chemother
  77. (1998). Staphylococcus aureus serotype 5 capsular polysaccharide is antiphagocytic and enhances bacterial virulence in a murine bacteremia model. Infect Immun
  78. (1997). The alternative sigma factor sigmaB in Staphylococcus aureus: regulation of the sigB operon in response to growth phase and heat shock. Arch Microbiol
  79. (1995). The anaerobic life of Bacillus subtilis: cloning of the genes encoding the respiratory nitrate reductase system.
  80. (1992). The crisis in antibiotic resistance.
  81. (2007). The proteome and transcriptome analysis of Bacillus subtilis in response to salicylic acid. Proteomics
  82. (2001). The srhSR gene pair from Staphylococcus aureus: genomic and proteomic approaches to the identification and characterization of gene function. Biochemistry
  83. (1996). Tomasz A: Sigma-B, a putative operon encoding alternate sigma factor of Staphylococcus aureus RNA polymerase: molecular cloning and DNA sequencing.
  84. (1990). Uncouplers of oxidative phosphorylation. Environ Health Perspect
  85. (2001). Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance. Lancet Infect Dis