Article thumbnail

Role of MicroRNAs in Insect Host–Microorganism Interactions

By Sassan Asgari

Abstract

MicroRNAs (miRNAs) have appeared as important regulators of various biological processes including development, cancer, immunity, and host–microorganism interactions. Accumulating evidence demonstrates the differential expression of host miRNAs upon infection by various microorganisms and the involvement of microorganism-encoded miRNAs in host manipulation. Some of these alterations could be part of a host response to an infection to limit replication and dissemination of the microorganism or, conversely, due to manipulation of the host miRNA pathway by the microorganism to facilitate its replication. Insights into the role of miRNAs in host defense responses and host manipulation by microorganisms will enable a better understanding of host–microorganism interactions

Topics: Physiology
Publisher: Frontiers Research Foundation
OAI identifier: oai:pubmedcentral.nih.gov:3155871
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles

Citations

  1. (2010). (2010).Identificationof microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus.
  2. (2005). 20-Hydroxyecdysone indirectly regulates Hemolin gene expression in Hyalophora cecropia.
  3. (2011). 6Asgari miRNAs in host–microorganism interactions Liver specific microRNA, miR-122, enhances the replication of hepatitis C virus in non-hepatic cells.
  4. (2011). 7Asgari miRNAs in host–microorganism interactions
  5. (2009). A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium.
  6. (2010). An ascovirus encoded ribonuclease III autoregulates its expression and suppresses RNAi-mediated gene silencing.
  7. (2008). An insect virusencoded microRNA regulates viral replication.
  8. and Hopkins,N.(2004).Identificationof 315genesessentialforearlyzebrafish development.
  9. andCherry,S.(2009).Ars2regulates bothmiRNA-andsiRNA-dependent silencing and suppresses RNA virus infection in Drosophila.
  10. (2007). Anopheles gambiae miRNAs as actors of defence reaction against Plasmodium invasion.
  11. (2009). Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.
  12. (2003). Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila.
  13. (2004). Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway.
  14. (2008). Cloning, characterization, and expression of microRNAs from the Asian malaria mosquito, Anopheles stephensi.
  15. (2003). Computational identification of Drosophila microRNA genes.
  16. (2011). Control of microRNA biogenesis and transcription by cell signaling pathways.
  17. (2009). Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and amulti-speciessurveyof novelmosquito miRNAs.
  18. (2010). Discovering microRNAs from Bombyx mori nucleopolyhedrosis virus.
  19. (2009). Distinct mechanisms for microRNA strand selection by Drosophila argonautes.
  20. (2004). Distinct roles for argonaute proteins in small RNA-directed RNA cleavage pathways.GenesDev.18,1655–1666.
  21. (2008). Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana.
  22. (2008). EBV microRNAs in primary lymphomas and targeting of CXCL-11 by
  23. (2011). Eimeria papillata: upregulation of specific miRNA-species in the mouse jejunum.
  24. (2008). Epstein-Barr virus latent membraneprotein1inducescellular microRNA miR-146a, a modulator of lymphocytesignalingpathways.J.
  25. (2009). Evidence for metabolic provisioning by a common invertebrate endosymbiont,Wolbachia pipientis, during periods of nutritional stress.PLoSPathog.5,e1000368.doi:
  26. (2004). Fast and effective prediction of microRNA/targetduplexes.RNA
  27. (2004). Fitness advantage and cytoplasmic incompatibility inWolbachia singleand superinfected Aedes albopictus.
  28. (2010). Functional analysis of a cellular microRNA in insect host-ascovirus interaction.
  29. (2010). Functional shifts in insect microRNA evolution.
  30. (2008). How many species are infected with Wolbachia? – A statistical analysis of current data.
  31. Identification of novel genes coding for small expressed RNAs.
  32. (2004). Identification of virus-encoded microRNAs.
  33. (2009). Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes.
  34. (2007). Interferon modulation of cellular microRNAs as an antiviral mechanism.
  35. (2007). Intronic microRNA precursors that bypass Drosha processing.
  36. (2009). Many roads to maturity: microRNA biogenesis pathways and their regulation.
  37. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth.
  38. (2006). MicroRNA biogenesis: isolation and characterization of the microprocessor complex.
  39. (2009). MicroRNA control in the immune system: basic principles.
  40. (2009). MicroRNA expression profiling during the life cycle of the silkworm (Bombyx mori).
  41. (2008). MicroRNA-10a binds the 5 UTR of ribosomal protein mRNAs and enhances their translation.
  42. (2008). microRNA-122 stimulates translationof hepatitisCvirusRNA.
  43. (2005). MicroRNA1 influences cardiac differentiation in Drosophila and regulates notch signaling.
  44. (2004). MicroRNAs and the regulation of celldeath.TrendsGenet.20,617–624.
  45. (2011). MicroRNAs in Drosophila development.
  46. (2007). MicroRNAs inviralreplicationandpathogenesis.
  47. (2009). MicroRNAs: target recognition and regulatory functions.
  48. (2011). miRBase: integrating microRNA annotation and deepsequencing data.
  49. (2009). Most mammalian mRNAs are conserved targets of microRNAs.
  50. (2006). Natural selection drives extremely rapid evolution in antiviral RNAi genes.
  51. (2009). NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses. PLoS Pathog.
  52. (2011). paper pending published: 12
  53. (2010). Regulation of mRNA translation and stability by microRNAs.Annu.Rev.Biochem.79,
  54. (2010). Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA.
  55. (2007). Removing endosymbiotic Wolbachia specifically decreases lifespan of females and competitiveness in a laboratory strain of Drosophila melanogaster.
  56. (2009). Revisiting the principles of microRNA target recognition and mode of action.
  57. (2011). Role of microRNAsininsecthost–microorganism interactions.
  58. (1999). Sequence analysis of the genome of Bombyx mori nucleopolyhdrovirus.
  59. (2008). Sequence relationships among C. elegans, D. melanogaster and human microRNAs highlight the extensive conservation of microRNAs in biology.
  60. (2009). Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti.
  61. (2003). Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broadcomplexgeneactivity.Dev.Biol.259,
  62. (2008). The Bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster.
  63. The native Wolbachia endosymbionts of Drosophila melanogaster and Culex quinquefasciatus increase host resistance to West Nile virus infection.
  64. (2008). The silkworm (Bombyx mori) microRNAs and their expressions in multiple developmental stages.
  65. (2003). The small RNA profile during Drosophila melanogater development.
  66. (2001). TheArabidopsisserrate geneencodes a zinc-finger protein required for normal shoot development.
  67. (2009). Viral suppressors of RNA silencing hinder exogenous and endogenous small RNA pathways in Drosophila. PLoS ONE 4,e5866. doi: 10.1371/journal.pone.0005866
  68. (2008). Wolbachia and virus protection in insects.
  69. (2002). Wolbachia density and virulence attenuation after transfer into a novel host.
  70. (2010). Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiae.
  71. (2011). Wolbachia utilizes host microRNAstomanipulatehostgene expression and facilitate colonization of the dengue vector Aedes aegypti.
  72. (1997). Wolbachia, normally a symbiont of Drosophila, can be virulent, causing degeneration and early death.
  73. (2008). Wolbachia: master manipulators of invertebrate biology.