In Vivo Conditional Pax4 Overexpression in Mature Islet β-Cells Prevents Stress-Induced Hyperglycemia in Mice
By Kai Hui Hu He, Petra I. Lorenzo, Thierry Brun, Carmen M. Jimenez Moreno, Deborah Aeberhard, Jorge Vallejo Ortega, Marion Cornu, Fabrizio Thorel, Asllan Gjinovci, Bernard Thorens, Pedro L. Herrera, Paolo Meda, Claes B. Wollheim and Benoit R. Gauthier
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The proportion of insulin 2 (□) and insulin + (■)c e l l sw a sc o u n t e d on the slides from A. C: Pancreatic sections from 3 months’ Pax4-overexpressing animals were coimmunostained for BrdU and Pdx-1. Cell counting was performed as
Total number of Pdx-1 + cells was counted on the slides from B.
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