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The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomes

By Christian J Wippo, Lars Israel, Shinya Watanabe, Andreas Hochheimer, Craig L Peterson and Philipp Korber


The molecular mechanisms involved in establishing nucleosome positions in vivo are not well understood. Here, RSC is specifically required for moving nucleosomes from their intrinsically preferred in vitro reconstituted locations to their physiologically relevant positions

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Publisher: Nature Publishing Group
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Provided by: PubMed Central
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