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Comparative genome analysis of a large Dutch Legionella pneumophila strain collection identifies five markers highly correlated with clinical strains

By Ed Yzerman, Jeroen den Boer, Martien Caspers, Arpit Almal, Bill Worzel, Walter van der Meer, Roy Montijn and Frank Schuren
Topics: Research Article
Publisher: BioMed Central
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Provided by: PubMed Central

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  1. (2007). Bonten MJ: Insertion sequence-driven diversification creates a globally dispersed emerging multiresistant subspecies of E. faecium. PLoS Pathog
  2. (2004). Buchrieser C: Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity. Nature Genet
  3. (2008). Buchrieser C: Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species. Genome Res
  4. (2007). CA: Comparison of clinical and environmental isolates of Legionella pneumophila obtained in the UK over 19 years. Clin Microbiol Infect
  5. (2007). Chinnaiyan AM: Feature Selection and Molecular Classification of Cancer Using Genetic Programming. Neoplasia
  6. Classification of Gene Expression Data with Genetic Programming.
  7. (2008). Classification with highdimensional genetic data: assigning patients and genetic features to known classes. Biom J
  8. Conyn-Van Spaendonck MA: A large outbreak of Legionnaires' disease at a flower show, the Netherlands,
  9. (2007). De Groot GM: Evaluation of the Dutch Water Supply Act: Legionella prevention.
  10. (2002). Emerg Infect Dis
  11. (2002). Falkow S: Improved analytical methods for microarray-based genome-composition analysis. Genome Biol
  12. (2004). Genetic programming for mining DNA chip data from cancer patients. Genetic Programming and Evolvable Machines
  13. (2001). LW: Symbolic Discriminant Analysis for Mining Gene Expression Patterns.
  14. (2001). Method and system for genetic programming.
  15. (1985). RB: Difference in virulence of environmental isolates of Legionella pneumophila.
  16. (2004). S: Clinical and environmental distributions of Legionella strains in France are different.
  17. (2005). S: Clinical and environmental isolates of Legionella pneumophila serogroup 1 cannot be distinguished by sequence analysis of two surface protein genes and three housekeeping genes. Appl Environ Microbiol
  18. (1993). Selecting a classification method by cross-validation. Machine Learning
  19. (1997). Smooth non-parametric receiver operating characteristic (ROC) curves for continuous diagnostic tests. Stat Med
  20. (2005). TG: Consensus sequence-based scheme for epidemiological typing of clinical and environmental isolates of Legionella pneumophila.
  21. (2002). TG: Designation of the European Working Group on Legionella Infection (EWGLI) amplified fragment length polymorphism types of Legionella pneumophila serogroup 1 and results of intercentre proficiency testing using a standard protocol.
  22. (2004). The genomic sequence of the accidental pathogen Legionella pneumophila. Science
  23. (2003). Thiagarajan M: TM4: a free, open-source system for microarray data management and analysis. Biotechniques
  24. (2006). Worzel WP: The use of genetic programming in the analysis of quantitative gene expression profiles for identification of nodal status in bladder cancer.
  25. (2007). WT: Determination of the relationship between group A streptococcal genome content, M type, and toxic shock syndrome by a mixed genome microarray. Infect Immun
  26. (2008). Yzerman EP: Genotypic comparison of clinical Legionella isolates and patientrelated environmental isolates in The Netherlands, 2002-2006. Clin Microbiol Infect