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3-Hydroxykynurenine Suppresses CD4+ T-Cell Proliferation, Induces T-Regulatory-Cell Development, and Prolongs Corneal Allograft Survival

By Sarah S. Zaher, Conrad Germain, Hongmei Fu, Daniel F. P. Larkin and Andrew J. T. George

Abstract

This work is of importance, not only because it explores the physiological role of kynurenines in controlling immune responses, but also because it opens the possibility of using kynurenine-like molecules as immunosuppressive therapy

Topics: Articles
Publisher: Association for Research in Vision and Ophthalmology, Inc.
OAI identifier: oai:pubmedcentral.nih.gov:3088555
Provided by: PubMed Central
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