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In Vitro Activity of Nifuratel on Vaginal Bacteria: Could It Be a Good Candidate for the Treatment of Bacterial Vaginosis?▿

By Giuseppe Togni, Valeria Battini, Anna Bulgheroni, Federico Mailland, Maurizio Caserini and Werner Mendling

Abstract

Bacterial vaginosis is characterized by a shift of the physiological flora to a diverse spectrum of bacteria, where Gardnerella vaginalis and Atopobium vaginae are the most important markers. In this study, the antimicrobial activity of nifuratel against G. vaginalis, A. vaginae, and lactobacilli was compared with that of the two currently used antibiotics metronidazole and clindamycin. Results suggest that nifuratel has a better spectrum of activity, being highly active against G. vaginalis and A. vaginae without affecting lactobacilli

Topics: Susceptibility
Publisher: American Society for Microbiology
OAI identifier: oai:pubmedcentral.nih.gov:3088278
Provided by: PubMed Central
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