Article thumbnail

Treatment of candidiasis: insights from host genetics

By C.E. Delsing, C.P. Bleeker-Rovers, B.J. Kullberg and M.G. Netea

Abstract

Candida species are major causes of mucosal and invasive infections, leading to substantial morbidity and mortality. Despite the development of new classes of antifungal drugs, mortality in patients with systemic candidiasis remains high. Host-Candida interaction plays an important role in effective elimination of the pathogen. Genetic studies have rendered important insights into antifungal host defense and have identified potential targets for adjunctive therapy. In this article, the authors review the genetic variations in the host defense to Candida and their implications for the treatment of mucosal and systemic candidiasis

Year: 2012
DOI identifier: 10.1586/eri.12.79
OAI identifier:
Provided by: NARCIS
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.loc.gov/mods/v3 (external link)
  • http://hdl.handle.net/2066/110... (external link)
  • http://hdl.handle.net/2066/110... (external link)
  • https://repository.ubn.ru.nl/d... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.