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JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress

By Juhong Liu, Hye-Jung Chung, Matthew Vogt, Yetao Jin, Daniela Malide, Liusheng He, Miroslav Dundr and David Levens

Abstract

USP29 joins the family of deubiquitinating enzymes involved in the stabilization of p53. Furthermore, p53 regulation is in this case linked to the c-Myc pathway, whose constituents JTV1 and FBP control USP29 expression upon oxidative stress

Topics: Article
Publisher: Nature Publishing Group
OAI identifier: oai:pubmedcentral.nih.gov:3049210
Provided by: PubMed Central
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