Article thumbnail

5-HT1A gene promoter polymorphism and [18F]MPPF binding potential in healthy subjects: a PET study

By Amélie Lothe, Claudette Boni, Nicolas Costes, Sandrine Bouvard, Philip Gorwood, Franck Lavenne, Marion Alvarez and Philippe Ryvlin
Topics: Research
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:2909987
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles

Citations

  1. (1994). AI: Quantitative autoradiography of 5-hydroxytryptamine1A binding sites in rats with chronic neonatal 5,7-dihydroxytryptamine lesions. Brain Res Dev Brain Res
  2. (2006). Altered serotonin 1A binding in major depression: a [carbonyl-C-11]WAY100635 positron emission tomography study. Biol Psychiatry
  3. (2001). B: A probabilistic atlas and reference system for the human brain: International Consortium for Brain Mapping (ICBM). Philos Trans R Soc Lond B Biol Sci
  4. (2007). Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab
  5. (1999). DE: A common C-1018G polymorphism in the human 5-HT1A receptor gene. Psychiatr Genet
  6. (2001). DeKosky ST: Gender-specific aging effects on the serotonin 1A receptor. Brain Res
  7. (2004). Descarries L: Toward brain imaging of serotonin 5-HT1A autoreceptor internalization. Neuroimage
  8. (1997). Diksic M: Differences between males and females in rates of serotonin synthesis in human brain. Proc Natl Acad Sci USA
  9. (2003). Displacement of the PET ligand 18F-MPPF by the electrically evoked serotonin release in the rat hippocampus. Synapse
  10. (1995). Frackowiak RJS: Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp
  11. (1991). Frackowiak RSJ: Comparing functional (PET) images: the assessment of significant changes.
  12. (2005). Grasby PM: A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans.
  13. (1998). Highyield radiosynthesis and preliminary in vivo evaluation of p-[18F]MPPF, a fluoro analog of WAY-100635. Nucl Med Biol
  14. (2008). Ibáñez V: In vivo quantification of 5-HT1A[18F]MPPF interactions in rats using the YAP-(S)PET scanner and a beta-microprobe. Neuroimage
  15. (2002). JF: Effect of endogenous serotonin on the binding of the 5-hT1A PET ligand 18FMPPF in the rat hippocampus: kinetic beta measurements combined with microdialysis.
  16. (2007). JK: Evolving knowledge of sex differences in brain structure, function, and chemistry. Biol Psychiatry
  17. (1998). KA: Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein. Mol Endocrinol
  18. (2005). Kaye WH: Relationship of a 5-HT transporter functional polymorphism to 5-HT1A receptor binding in healthy women. Mol Psychiatry
  19. (1994). Kung HF: Derivatives of 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl-p-iodobenzamido)ethyl]pipera zine (p-MPPI) as 5-HT1A ligands.
  20. (1998). Lammertsma AA: Tracer kinetic modeling of the 5-HT1A receptor ligand [carbonyl-11C]WAY-100635 for PET. Neuroimage
  21. (2005). Le Bars D: A 18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging.
  22. (2002). Le Bars D: Modeling [18F]MPPF positron emission tomography kinetics for the determination of 5-hydroxytryptamine(1A) receptor concentration with multiinjection.
  23. (2004). Lemonde S: 5-HT1A receptors, gene repression, and depression: guilt by association. Neuroscientist
  24. (2005). Ober C: Sex-specific genetic architecture of whole blood serotonin levels.
  25. (2007). Parametric and regional maps of free serotonin 5HT1A receptor sites in human brain as function of age in healthy humans. Neuropsychopharmacology
  26. (2009). Parsey RV: Positron emission tomography quantification of serotonin-1A receptor binding in medication-free bipolar depression. Biol Psychiatry
  27. (2003). PR: Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide.
  28. (1986). Quantitative autoradiography of multiple 5-HT1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats.
  29. (2005). Regional heterogeneity of 5-HT1A receptors in human cerebellum as assessed by positron emission tomography. J Cereb Blood Flow Metab
  30. (2009). Ryvlin P: Association between triallelic polymorphism of the serotonin transporter and [18F]MPPF binding potential at 5-HT1A receptors in healthy subjects. Neuroimage
  31. (2001). S: Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET. Neuropsychopharmacology
  32. (1990). Soudijn W: The concept of selectivity in 5-HT receptor research.
  33. (2001). The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation. Nat Struct Biol
  34. (1995). The selective 5-HT1A antagonist radioligand [3H]WAY 100635 labels both G-proteincoupled and free 5-HT1A receptors in rat brain membranes.
  35. (2006). Tsai SJ: Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder. Pharmacogenomics J
  36. (2008). Zubieta JK: Monoamine oxidase A genotype predicts human serotonin 1A receptor availability in vivo.