Article thumbnail

Large-Scale Evidence for Conservation of NMD Candidature Across Mammals

By David A. de Lima Morais and Paul M. Harrison
Topics: Research Article
Publisher: Public Library of Science
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (2003). [New oncological treatment principle with imatinib].
  2. (2009). Alternative splicing and disease.
  3. (2002). Alternative splicing and genome complexity.
  4. (2006). Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges.
  5. (2005). Automated generation of heuristics for biological sequence comparison.
  6. (2005). BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments.
  7. (1999). BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences.
  8. (2008). Computational analysis of splicing errors and mutations in human transcripts.
  9. (1996). Cytoplasmic mRNA for human triosephosphate isomerase is immune to nonsense-mediated decay despite forming polysomes.
  10. (2004). Detection and evaluation of intron retention events in the human transcriptome.
  11. (2003). Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking
  12. (2008). E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35.
  13. (2004). ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes.
  14. (2003). Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans.
  15. (1995). Exon recognition in vertebrate splicing.
  16. (2003). Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.
  17. (2009). Genomic evidence for non-random endemic populations of decaying exons from mammalian genes.
  18. (2005). GMAP: a genomic mapping and alignment program for mRNA and EST sequences.
  19. (2007). Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism.
  20. (2009). KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res.
  21. (2000). Modification of alternative splicing pathways as a potential approach to chemotherapy.
  22. (2009). Noisy splicing, more than expression regulation, explains why some exons are subject to nonsensemediated mRNA decay.
  23. (2005). Non-EST based prediction of exon skipping and intron retention events using Pfam information.
  24. (2005). Nonsense mutations: running the red light.
  25. (2004). Nonsense-mediated decay approaches the clinic.
  26. (2004). Pharmacologic therapy for stop mutations: how much CFTR activity is enough?
  27. (2005). Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.
  28. (2008). Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay.
  29. (1999). Ribosomal protein S14 of Saccharomyces cerevisiae regulates its expression by binding to RPS14B pre-mRNA and to 18S rRNA.
  30. (2004). Ribosomal proteins S13 and L23 promote multidrug resistance in gastric cancer cells by suppressing druginduced apoptosis.
  31. (1998). Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption.
  32. (2002). Splice variation in mouse full-length cDNAs identified by mapping to the mouse genome.
  33. (2006). Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma.
  34. (1994). The ancient regulatory-protein family of WD-repeat proteins.
  35. (2004). The Gene Ontology (GO) database and informatics resource.
  36. (2009). The mammalian nonsense-mediated mRNA decay pathway: to decay or not to decay! Which players make the decision?
  37. (2007). The nonsense-mediated decay RNA surveillance pathway.
  38. (2010). The Proteomics Identifications database:
  39. (2000). The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.
  40. (2008). The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation.
  41. (2008). Translational control of intron splicing in eukaryotes.
  42. (2007). Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements.
  43. (2000). Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C.
  44. (2003). Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes.