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CwpFM (EntFM) Is a Bacillus cereus Potential Cell Wall Peptidase Implicated in Adhesion, Biofilm Formation, and Virulence▿

By Seav-Ly Tran, Elisabeth Guillemet, Michel Gohar, Didier Lereclus and Nalini Ramarao

Abstract

Bacillus cereus EntFM displays an NlpC/P60 domain, characteristic of cell wall peptidases. The protein is involved in bacterial shape, motility, adhesion to epithelial cells, biofilm formation, vacuolization of macrophages, and virulence. These data provide new information on this, so far, poorly studied toxin and suggest that this protein is a cell wall peptidase, which we propose to rename CwpFM

Topics: Molecular Biology of Pathogens
Publisher: American Society for Microbiology (ASM)
OAI identifier: oai:pubmedcentral.nih.gov:2863573
Provided by: PubMed Central
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