Presence of High-Risk HPV mRNA in Relation to Future High-Grade Lesions among High-Risk HPV DNA Positive Women with Minor Cytological Abnormalities.

Johansson, Hanna K; Bjelkenkrantz, Kaj; Darlin, Lotten; Dillner, Joakim; Forslund, Ola

oai:lup.lub.lu.se:6cda242e-2841-487f-83af-3e001820c58a

Presence of High-Risk HPV mRNA in Relation to Future High-Grade Lesions among High-Risk HPV DNA Positive Women with Minor Cytological Abnormalities.

Authors: Hanna K Johansson
Kaj Bjelkenkrantz
Lotten Darlin
Joakim Dillner
Ola Forslund
Publication date: 1 January 2015
Publisher: Public Library of Science (PLoS)
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Abstract

Continuous expression of E6- and E7-oncogenes of high-risk human papillomavirus (HPV) types is necessary for the development and maintenance of the dysplastic phenotype. The aim of the study was to determine the sensitivity and specificity of the APTIMA HPV mRNA assay (Hologic) in predicting future development of high-grade cervical intraepithelial neoplasia (CIN) among high-risk HPV-DNA-positive women with atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous epithelial lesion (LSIL) cytology

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Lund University Publications

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Last time updated on 18/06/2017

This paper was published in Lund University Publications.

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