Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

Kahn, Robin; Berthold, Elisabet; Gullstrand, Birgitta; Schmidt, Tobias; Kahn, Fredrik; Geborek, Pierre; Saxne, Tore; Bengtsson, Anders; Månsson, Bengt

oai:lup.lub.lu.se:fb3356fd-8733-49f9-8165-738293d5b3b2

Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

Authors: Robin Kahn
Elisabet Berthold
Birgitta Gullstrand
Tobias Schmidt
Fredrik Kahn
Pierre Geborek
Tore Saxne
Anders Bengtsson
Bengt Månsson
Publication date: 1 January 2016
Publisher: Wiley-Blackwell
Doi

Abstract

The relationship between tumour necrosis factor-alpha (TNF-α) and drug survival had not been studied in juvenile idiopathic arthritis (JIA) and there were no laboratory tests to predict the long-term efficacy of biological drugs for JIA. We studied if serum levels of TNF-α, free or bound to etanercept, could predict long-term efficacy of etanercept in children with JIA

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Lund University Publications

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Last time updated on 18/06/2017

This paper was published in Lund University Publications.

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