Skip to main content
Article thumbnail
Location of Repository

MRI of Neurosyphilis Presenting as Mesiotemporal Abnormalities: a Case Report

By Yu Mi Jeong, Hee Young Hwang and Hyung Sik Kim


The high signal intensities in bilateral mesiotemporal lobes on T2-weighted images are typical findings of herpes encephalitis or paraneoplastic limbic encephalitis. We report a case of neurosyphilis with mesiotemporal involvement on MRI. Positive antibodies in the cerebrospinal fluid confirmed the diagnosis. The results suggest that neurosyphilis should be considered when MRI results indicate mesiotemporal abnormalities

Topics: Case Report
Publisher: The Korean Society of Radiology
OAI identifier:
Provided by: PubMed Central

Suggested articles


  1. (1999). A 51-year-old woman with disorientation and amnesia. Lancet
  2. CT and MR findings in HIV-negative neurosyphilis.
  3. Go ¨ulao A. Differential diagnosis of mesiotemporal lesions: case report of neurosyphilis.
  4. (1993). Herpesvirus infections of the CNS: MR findings.
  5. Mesiotemporal T2-weighted hyperintensity: neurosyphilis mimicking herpes encephalitis.
  6. Neurosyphilis and paraneoplastic limbic encephalitis: important differential diagnoses.
  7. Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings.
  8. Neurosyphilis presenting as herpes simplex encephalitis.
  9. Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.
  10. (2002). Symptomatic early neurosyphilis among HIV-positive men who have sex with men—four cities, United States,

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.