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In silico prioritisation of candidate genes for prokaryotic gene function discovery: an application of phylogenetic profiles

By Frank PY Lin, Enrico Coiera, Ruiting Lan and Vitali Sintchenko
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:2669486
Provided by: PubMed Central
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    Citations

    1. A similarity-based method for genome-wide prediction of disease-relevant human genes. Bioinformatics 2002, 18(Suppl 2):S110–115.
    2. A tree kernel to analyse phylogenetic profiles. Bioinformatics 2002, 18(Suppl 1):S276–84.
    3. (2004). and Ouzounis CA: Genome-wide identification of genes likely to be involved in human genetic disease. Nucleic Acids Res
    4. (2007). Annotation, comparison and databases for hundreds of bacterial genomes. Res Microbiol
    5. Assigning protein functions by comparative genome analysis: protein phylogenetic profiles.
    6. (2002). Association of genes to genetically inherited diseases using data mining. Nat Genet
    7. (2006). Bacterial genomics and pathogen evolution. Cell
    8. (1999). Biochemical pathways: An Atlas of Biochemistry and Molecular Biology Hoboken, NJ; Wiley-Spektrum;
    9. Data Mining: Practical machine learning tools and techniques
    10. (2005). Exploring relationships and mining data with the UCSC Gene Sorter. Genome Res
    11. (2006). Gene prioritization through genomic data fusion. Nat Biotechnol
    12. (2000). KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res
    13. (2006). Localizing proteins in the cell from their phylogenetic profiles.
    14. (2007). Mohlke KL and Vision TJ: A computational system to select candidate genes for complex human traits. Bioinformatics
    15. (2007). Multidimensional annotation of the Escherichia coli K-12 genome. Nucleic Acids Res
    16. NCBI bacterial genomes catalogue file. ftp://ftp.ncbi.nih.gov/ genomes/Bacteria/.
    17. (2005). Phylogenetic detection of conserved gene clusters in microbial genomes.
    18. (2003). POCUS: mining genomic sequence annotation to predict disease genes. Genome Biol
    19. (2004). Protein network inference from multiple genomic data: a supervised approach. Bioinformatics
    20. (2007). Przytycka TM and Aravind L: Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive assessment.
    21. (1991). Regulation of gene expression in fermentative and respiratory systems in Escherichia coli and related bacteria. Annu Rev Genet
    22. (2005). Speeding disease gene discovery by sequence based candidate prioritization.
    23. (2006). SUSPECTS: enabling fast and effective prioritization of positional candidates. Bioinformatics
    24. (1995). The minimal gene complement of Mycoplasma genitalium.
    25. (2000). Who's your neighbor? New computational approaches for functional genomics. Nat Biotechnol

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