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TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women123

By Marilyn C Cornelis, Lu Qi, Peter Kraft and Frank B Hu

Abstract

Background: TCF7L2 is the strongest type 2 diabetes (T2D) locus identified to date, and evidence suggests it plays an important role in insulin synthesis, processing, and secretion. Dietary factors that increase the insulin demand might enhance the risk of T2D associated with TCF7L2 variants

Topics: Gene-Nutrient Interactions
Publisher: American Society for Nutrition
OAI identifier: oai:pubmedcentral.nih.gov:2667467
Provided by: PubMed Central
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