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Mixed Candida albicans strain populations in colonized and infected mucosal tissues

By Mette D Jacobsen, Amanda D Duncan, Judith Bain, Elizabeth M Johnson, Julian R Naglik, Duncan J Shaw, Neil AR Gow and Frank C Odds

Abstract

Multilocus sequence typing of six Candida albicans colonies from primary isolation plates revealed instances of colony-to-colony microvariation and carriage of two strain types in single oropharyngeal and vaginal samples. Higher rates of colony variation in commensal samples suggest selection of types from mixed populations either in the shift to pathogenicity or the response to antifungal treatment

Topics: Research Articles
Publisher: Blackwell Publishing Ltd
OAI identifier: oai:pubmedcentral.nih.gov:2667310
Provided by: PubMed Central
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