Skip to main content
Article thumbnail
Location of Repository

Chikungunya Virus and Central Nervous System Infections in Children, India

By Penny Lewthwaite, Ravi Vasanthapuram, Jane C. Osborne, Ashia Begum, Jenna L.M. Plank, M. Veera Shankar, Roger Hewson, Anita Desai, Nick J. Beeching, Ravi Ravikumar and Tom Solomon

Abstract

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus best known for causing fever, rash, arthralgia, and occasional neurologic disease. By using real-time reverse transcription–PCR, we detected CHIKV in plasma samples of 8 (14%) of 58 children with suspected central nervous system infection in Bellary, India. CHIKV was also detected in the cerebrospinal fluid of 3 children

Topics: Dispatch
Publisher: Centers for Disease Control and Prevention
OAI identifier: oai:pubmedcentral.nih.gov:2662654
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    Citations

    1. (2007). A single mutation in Chikungunya virus affects vector specifi city and epidemic potential. PLoS Pathogens.
    2. (1971). Acute neurologic and sensorial disorders in dengue and chikungunya fever. Bull Soc Pathol Exot Filiales.
    3. (2007). an epidemic arbovirosis. Lancet Infect Dis.
    4. Antibodies against prM protein distinguish between previous infection with dengue and Japanese encephalitis viruses.
    5. (2006). Chikungunya outbreaks caused by African genotype, India. Emerg Infect Dis.
    6. (2008). Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come? Virol J.
    7. (2008). Current use and development of vaccines for Japanese encephalitis. Expert Opin Biol Ther.
    8. (2004). Detection of Australasian fl avivirus encephalitic viruses using rapid fl uorogenic TaqMan RT-PCR assays. J Virol Methods.
    9. (2006). Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak. PLoS Med.
    10. Global Advisory Committee on Vaccine Safety,
    11. Guillain-Barré syndrome complicating a Chikungunya virus infection.
    12. (2008). Increased mortality rate associated with chikungunya epidemic, Ahmedabad, India. Emerg Infect Dis.
    13. (2007). MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol.
    14. Molecular diagnosis and analysis of Chikungunya virus.
    15. (2007). Neurologic complications in Chikungunya fever.
    16. Neurologic manifestations of pediatric Chikungunya infection.
    17. (2006). Novel chikungunya virus variant in travelers returning from Indian Ocean islands. Emerg Infect Dis.
    18. Virological investigation of cases with neurological complications during the outbreak of haemorrhagic fever in Calcutta.
    19. (2007). Wkly Epidemiol Rec.

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.