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A comparative study of two methods for attaining constant alcohol levels

By Remco W M Zoethout, Joop M A van Gerven, Glenn J H Dumont, Sunita Paltansing, Nathalie D van Burgel, Monique van der Linden, Albert Dahan, Adam F Cohen and Rik C Schoemaker


WHAT IS ALREADY KNOWN ABOUT THIS SUBJECTIn determining the effects of alcohol or assessing alcohol–drug interactions, it is helpful if the alcohol plasma concentration can be maintained at reasonably stable levels.To achieve pseudo-steady state alcohol concentrations various methods are used.In this study two different methods were optimized and compared in the search for an accurate method to maintain constant alcohol levels for a prolonged period of time

Topics: Methods in Clinical Pharmacology
Publisher: Blackwell Science Inc
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Provided by: PubMed Central
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