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Dramatic response of a gastrointestinal stromal tumor to neadjuvant imatinib therapy

By Shohrat Annaberdyev, Joseph Gibbons and Jeffrey M Hardacre


Gastrointestinal stromal tumors (GISTs) are the most common sarcoma of the alimentary tract and are believed to derive from the interstitial Cell of Cajal. Imatinib mesylate (Gleevec®; Novartis, Basel, Switzerland) has revolutionized the treatment of GISTs and is generally used in the metastatic and adjuvant settings. We report the case of a 61-year old man who was treated with neoadjuvant imatinib for a massive gastric GIST with the hope of avoiding a potential multi-visceral resection

Topics: Case Report
Publisher: BioMed Central
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Provided by: PubMed Central

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