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Shhh! Silencing by microRNA-155

By Grace Teng and F. Nina Papavasiliou

Abstract

Small RNAs mediate a diverse pot-pourri of post-transcriptional silencing mechanisms, ranging from ‘classical’ RNA interference (RNAi), to gene repression by microRNAs (miRNAs), to maintenance of genomic stability by repeat-associated small RNAs. Here, we review recent findings on the function of miR-155, particularly its roles in mammalian innate and adaptive immunity, viral infection and oncogenesis

Topics: Review
Publisher: The Royal Society
OAI identifier: oai:pubmedcentral.nih.gov:2660923
Provided by: PubMed Central
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