Skip to main content
Article thumbnail
Location of Repository

ER stress affects processing of MHC class I-associated peptides

By Diana P Granados, Pierre-Luc Tanguay, Marie-Pierre Hardy, √Čtienne Caron, Danielle de Verteuil, Sylvain Meloche and Claude Perreault
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:2657905
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    Citations

    1. (1987). A simple method to eliminate the antigenicity of surface class I MHC molecules from the membrane of viable cells by acid treatment at pH 3. J Immunol Methods
    2. (2002). A: Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway.
    3. (2005). All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway. Immunol Rev
    4. (2005). C: T cells targeted against a single minor histocompatibility antigen can cure solid tumors. Nat Med
    5. (2006). Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol
    6. (2007). Chevet E: Integrated endoplasmic reticulum stress responses in cancer. Cancer Res
    7. (2006). Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. Cell
    8. (1998). Cresswell P: Mechanisms of MHC class I-restricted antigen processing. Annu Rev Immunol
    9. (2005). CV: Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation. Mol Biol Cell
    10. (2005). de Sousa M: HFE cross-talks with the MHC class I antigen presentation pathway. Blood
    11. (2008). Differential effects of a saturated and a monounsaturated fatty acid on MHC class I antigen presentation.
    12. (2008). Differential regulation of the ER stress response by long-chain fatty acids in the pancreatic beta-cell. Biochem Soc Trans
    13. (2004). Diverse and specific gene expression responses to stresses in cultured human cells. Mol Biol Cell
    14. (2002). Eisenlohr LC: Efficient and qualitatively distinct MHC class I-restricted presentation of antigen targeted to the endoplasmic reticulum.
    15. (1999). Eisenlohr LC: The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained.
    16. (2006). Endoplasmic reticulum stress signaling in disease. Physiol Rev
    17. (2005). ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth.
    18. (1998). et al.: Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. Proc Natl Acad Sci USA
    19. (1995). Generation, translocation, and presentation of MHC class I-restricted peptides. Annu Rev Biochem
    20. (2003). Glimcher LH: XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol
    21. (2003). Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function.
    22. (2007). Golovina TN: Rethinking peptide supply to MHC class I molecules. Nat Rev Immunol
    23. (1993). Hammerling GJ: Selective and ATPdependent translocation of peptides by the MHC-encoded transporter. Science
    24. (2006). Hegde RS: Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway. Cell
    25. (2008). Hotamisligil GS: Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis. Mol Cell
    26. (1996). Identification of an immunodominant mouse minor histocompatibility antigen (MiHA). T cell response to a single dominant MiHA causes graft-versus-host disease.
    27. (1993). Identification of Tcell epitopes: rapid isolation of class I-presented peptides from viable cells by mild acid elution. J Immunother Emphasis Tumor Immunol
    28. (2006). JE: Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death.
    29. (2004). JL: Targeting plasmid-encoded proteins to the antigen presentation pathways. Immunol Rev
    30. (2003). K: A time-dependent phase shift in the mammalian unfolded protein response. Dev Cell
    31. (2001). K: XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell
    32. (1997). KL: Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide. Proc Natl Acad Sci USA
    33. (2007). Lederkremer GZ: ER stress induces alternative nonproteasomal degradation of ER proteins but not of cytosolic ones. Cell Stress Chaperones
    34. (2003). Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol
    35. (2000). MB: Formation and kinetics of MHC class I-ovalbumin peptide complexes on immature and mature murine dendritic cells.
    36. (2006). Nicchitta CV: The DRiP hypothesis decennial: support, controversy, refinement and extension. Trends Immunol
    37. (2006). Obesity and infection. Lancet Infect Dis
    38. (1997). Ostrand-Rosenberg S: Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity. Proc Natl Acad Sci USA
    39. (2000). Ostrand-Rosenberg S: Tumor cells present MHC class II-restricted nuclear and mitochondrial antigens and are the predominant antigen presenting cells in vivo.
    40. (2007). Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes.
    41. (2003). Pamer EG: CD8 T cell responses to infectious pathogens. Annu Rev Immunol
    42. (2000). Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell
    43. (2007). Plumbing the sources of endogenous MHC class I peptide ligands. Curr Opin Immunol
    44. (1998). Popkin BM: Dietary fat intake does affect obesity!
    45. (2007). Prediction of graft-versus-host disease in humans by donor gene-expression profiling. PLoS Med
    46. (2006). regulated by the mammalian unfolded protein response and are required for ER-associated degradation.
    47. (2005). RJ: The mammalian unfolded protein response. Annu Rev Biochem
    48. (1997). RN: Localization, quantitation, and in situ detection of specific peptideMHC class I complexes using a monoclonal antibody. Immunity
    49. (2003). Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol
    50. (1993). Rotzschke O: Peptides naturally presented by MHC class I molecules. Annu Rev Immunol
    51. (2000). S: Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms.
    52. (2006). Sadighi Akha AA, Raden D, Kaufman RJ: Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol
    53. (2006). Samali A: Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep
    54. (2007). Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol
    55. (2006). Sonenberg N: mTOR, translation initiation and cancer. Oncogene
    56. (2005). Sonenberg N: Translational control in stress and apoptosis. Nat Rev Mol Cell Biol
    57. (2004). Sonenberg N: Upstream and downstream of mTOR. Genes Dev
    58. (2007). Stimulation of an unfolded protein response impairs MHC class I expression.
    59. (2003). Stress management: MHC class I and class I-like molecules as reporters of cellular stress. Immunity
    60. (2009). T cell sensing of antigen dose governs interactive behavior with dendritic cellsBMC Immunology
    61. (2007). The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell
    62. (2005). The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress. Methods
    63. (2008). The MHC class I peptide repertoire is molded by the transcriptome. J Exp Med
    64. (2005). The structure and location of SIMP/STT3B account for its prominent imprint on the MHC I immunopeptidome. Int Immunol
    65. (2004). Unanticipated antigens: translation initiation at CUG with leucine. PLoS Biol
    66. (2006). Weissman JS: Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science
    67. (2004). WH: The immune response under stress: the role of HSP-derived peptides. Trends Immunol
    68. (2008). Why T cells of thymic versus extrathymic origin are functionally different.
    69. (2006). Yewdell JW: Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products.

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.