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Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients

By Samy L Habib
Topics: Research
Publisher: BioMed Central
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Provided by: PubMed Central

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  1. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem
  2. (2008). Abboud HE: Tuberin Regulates the DNA Repair Enzyme OGG1.
  3. (2000). Boiteux S: Expression of the Fpg protein of Escherichia coli in Saccharomyces cerevisiae: effects on spontaneous mutagenesis and sensitivity to oxidative DNA damage. Biochimie
  4. (1998). Boiteux S: Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours. Oncogene
  5. (2002). Cantley LC: Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol Cell
  6. (2002). Cheng JQ: Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin.
  7. (1999). DE: Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci USA
  8. (2003). Dogliotti E: 8-Oxoguanine DNA damage: at the crossroad of alternative repair pathways. Mutat Res
  9. (1984). Edelbrock HH: Renal tumors associated with tuberous sclerosis: the case for aggressive surgical management.
  10. (1996). Embryonic neuronal markers in tuberous sclerosis: single-cell molecular pathology.
  11. (1991). Epidemiology of tuberous sclerosis.
  12. (2006). Hamartin and tuberin working together for tumour suppression.
  13. (2006). Henske EP: Hyperphosphorylation of ribosomal protein S6 in lymphangioleiomyomatosis-associated angiomyolipomas. Mod Pathol
  14. (1998). Henske EP: Malignant tumors of the kidney, brain, and soft tissues in children and young adults with the tuberous sclerosis complex. Cancer
  15. (2005). Henske EP: Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease. Oncogene
  16. (2004). HJ: Transcription factors NF-YA regulate the induction of human OGG1 following DNA-alkylating agent methylmethane sulfonate (MMS) treatment.
  17. (2001). JR: Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas.
  18. (2000). Kallioniemi A: Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis.
  19. (1987). Kelalis PP: Renal lesions in tuberous sclerosis.
  20. (2002). KL: TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol
  21. (2000). Radicella JP: Alterations of the DNA repair gene OGG1 in human clear cell carcinomas of the kidney. Cancer Res
  22. (2000). Radicella JP: Characterization of the hOGG1 promoter and its expression during the cell cycle. Mutat Res
  23. (2000). Radicella JP: The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis. Arch Biochem Biophys
  24. (2003). SS: Reduced constitutive 8-oxoguanine-DNA glycosylase expression and impaired induction following oxidative DNA damage in the tuberin deficient Eker rat. Carcinogenesis
  25. (2004). Toyokuni S: Role of reactive oxygen species in skin carcinogenesis. Antioxid Redox Signal
  26. (2008). Tuberin Haploinsufficiency is Associated with the Loss of OGG1 in Rat Kidney Tumors. Molecular Cancer
  27. (2005). Yeung RS: Aberrant beta-catenin signaling in tuberous sclerosis.
  28. (2002). Yeung RS: Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. Cancer Res
  29. (2003). Yeung RS: The tuberin-hamartin complex negatively regulates beta-catenin signaling activity.

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