Skip to main content
Article thumbnail
Location of Repository

The BARD1 C-Terminal Domain Structure and Interactions with Polyadenylation Factor CstF-50†

By Ross A. Edwards, Megan S. Lee, Susan E. Tsutakawa, R. Scott Williams, John A. Tainer and J. N. Mark Glover
Topics:
Publisher: American Chemical Society
OAI identifier: oai:pubmedcentral.nih.gov:2654182
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    Citations

    1. (2008). 11455ankyrin repeat domain and its functional consequences.
    2. (2006). A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA.
    3. (1997). A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
    4. (2001). Automated matching of high- and low-resolution structural models.
    5. (2001). BACH1, a novel helicaselike protein, interacts directly with BRCA1 and contributes to its DNA repair function.
    6. (2005). BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase.
    7. (2003). Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitinligase complex.
    8. (1999). Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage.
    9. (2004). BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.
    10. (2002). BRCA1-dependent and independent functions of BARD1.
    11. (2005). BRCA1/BARD1 inhibition of mRNA 3′ processing involves targeted degradation of RNA polymerase II.
    12. (2003). BRCT repeats as phosphopeptide-binding modules involved in protein targeting.
    13. (2001). Capping, splicing, and 3′ processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD.
    14. (2007). CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.
    15. (2007). CCDC98 targets BRCA1 to DNA damage sites.
    16. (1999). Compactness of the denatured state of a fast-folding protein measured by submillisecond small-angle x-ray scattering.
    17. (2000). Complex protein interactions within the human polyadenylation machinery identify a novel component.
    18. (2002). Consensusderived structural determinants of the ankyrin repeat motif.
    19. (2004). Coot: model-building tools for molecular graphics.
    20. (1996). Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
    21. (2001). Crystal structure of the BRCT repeat region from the breast cancerassociated protein BRCA1.
    22. (1998). Crystallography & NMR system: A new software suite for macromolecular structure determination.
    23. (2001). Determination of domain structure of proteins from X-ray solution scattering.
    24. (1992). Determination of the regularization parameter in indirect-transform methods using perceptual criteria.
    25. (2007). Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.
    26. (2006). DNA damage-induced BARD1 phosphorylation is critical for the inhibition of messenger RNA processing by BRCA1/BARD1 complex.
    27. (2002). Domain fishing: a first step in protein comparative modelling.
    28. (2001). Enhancement of protein modeling by human intervention in applying the automatic programs 3D-JIGSAW and 3DPSSM. Proteins Suppl.
    29. (1997). From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair.
    30. (2003). Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2.
    31. (1999). Functional interaction of BRCA1-associated BARD1 with polyadenylation factor
    32. (2002). Germline mutations of the BRCA1-associated ring domain (BARD1) gene in breast and breast/ovarian families negative for BRCA1 and BRCA2 alterations.
    33. (2005). Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancer.
    34. (1996). Identification of a RING protein that can interact in vivo with the BRCA1 gene product.
    35. (2001). Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis.
    36. (2004). Interactions between BRCT repeats and phosphoproteins: tangled up in two.
    37. (2005). MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.
    38. (1999). Model building by comparison at CASP3: using expert knowledge and computer automation.
    39. (2004). Molecular functions of BRCA1 in the DNA damage response.
    40. (1997). MOLREP: an automated program for molecular replacement.
    41. (1998). Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers.
    42. (2008). Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
    43. (2003). Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.
    44. (2003). PRIMUS: a Windows PC-based system for small-angle scattering data analysis.
    45. (1997). Refinement of macromolecular structures by the maximumlikelihood method.
    46. (1999). Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing.
    47. (1982). Small Angle X-Ray Scattering,
    48. (2003). Small-angle scattering studies of biological macromolecules in solution.
    49. (2007). Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography.
    50. (2004). Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1.
    51. (2007). Structural characterization of flexible proteins using small-angle X-ray scattering.
    52. (2008). Structural characterization of the active and inactive states of Src kinase in solution by small-angle X-ray scattering.
    53. (2003). Structural consequences of a cancer-causing BRCA1-BRCT missense mutation.
    54. (2007). Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair.
    55. (2004). Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer.
    56. (2001). Structure of a BRCA1-BARD1 heterodimeric RINGRING complex.
    57. (2005). Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail.
    58. (2004). Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling.
    59. (2008). The 3′ processing factor CstF functions in the DNA repair response. Nucleic Acids Res.
    60. (2004). The ankyrin repeat as molecular architecture for protein recognition.
    61. (1999). The ankyrin repeat: a diversity of interactions on a common structural framework.
    62. (2001). The BARD1-CstF-50 interaction links mRNA 3′ end formation to DNA damage and tumor suppression.
    63. (2003). The BRCT domain is a phospho-protein binding domain.
    64. (1998). The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression.
    65. (1997). The C-terminal domain of RNA polymerase II couples mRNA processing to transcription.
    66. (2007). The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA.
    67. (2003). Uniqueness of ab initio shape determination in small-angle scattering.
    68. (2001). Use of TLS parameters to model anisotropic displacements in macromolecular refinement.
    69. (2001). Using Situs for the registration of protein structures with low-resolution bead models from X-ray solution scattering.
    70. (2007). X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution.

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.