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Effect of Renin Angiotensin System Blockade on Pentraxin 3 Levels in Type-2 Diabetic Patients With Proteinuria

By Mahmut Ilker Yilmaz, Jonas Axelsson, Alper Sonmez, Juan Jesus Carrero, Mutlu Saglam, Tayfun Eyileten, Kayser Caglar, Alper Kirkpantur, Turgay Celik, Yusuf Oguz, Abdulgaffar Vural, Mujdat Yenicesu, Bengt Lindholm and Peter Stenvinkel

Abstract

Background and objectives: Long pentraxin 3 (PTX3) is a multimeric inflammatory mediator. Increased serum PTX3 levels have been reported among end-stage renal disease patients. Moreover, PTX3 has been suggested to represent a novel mortality risk factor, and elevated PTX3 levels have been shown to accompany increased albuminuria among patients with chronic kidney disease (CKD)

Topics: Chronic Kidney Disease
Publisher: American Society of Nephrology
OAI identifier: oai:pubmedcentral.nih.gov:2653664
Provided by: PubMed Central
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