journal articlereview
oaidoi:10.1016/j.cell.2008.04.027

Poised RNA Polymerase II Gives Pause for Thought

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Publication date
16 May 2008
Publisher
Elsevier Inc.
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    Abstract

    Transcription by RNA polymerase II (Pol II) is thought to be predominantly regulated by recruitment of Pol II to promoters. Recent genome-wide analyses demonstrate that many genes are in fact regulated after recruitment of Pol II, by mechanisms such as pausing of Pol II proximal to promoters

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