Vasopressin: A look at dialysis hypertension and autonomic dysfunction

Abstract

Dialysis hypertension is a complex disorder in which ambient vascular resistance is too high for the blood volume. van der Zee et al. remind us that this is contingent upon the endothelium itself, and that endothelial dysfunction is integral to uremia. Thus, while vasopressin may not abolish dialysis hypotension, its effects highlight the influence of uremia on the autocrine and neuroendocrine control of cardiovascular physiology