journal articlereview
oaidoi:10.1016/j.immuni.2005.12.007

IL-1 Can Act as Number One

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Publication date
31 January 2006
Publisher
Elsevier Inc.
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    Abstract

    Both interleukin-1 receptor (IL-1R) and toll-like receptor 2 (TLR2) signal via the adapter molecule MyD88. However, in response to a cutaneous infection challenge, the downstream signaling events diverge and IL-1R, but not TLR2, proves to be essential for host defense

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