journal article
oaidoi:10.1038/jid.2013.50

Recapitulating Atopic Dermatitis in Three Dimensions: Cross Talk between Keratinocytes and Nerve Fibers

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Publication date
30 June 2013
Publisher
The Society for Investigative Dermatology, Inc.
Doi

    Abstract

    Roggenkamp et al. (2013) report a significant advance in the in vitro reconstruction of atopic dermatitis (AD) by coculturing lesional human keratinocytes with sensory nerve fibers. This work has important implications for understanding the interaction between the resident skin cells and the peripheral nervous system in AD, and it sheds light on the pathways leading to the pruritus that typifies this disease

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