journal article
oaidoi:10.1016/0014-5793(85)81298-9

Murine interleukin 1 stimulates α2-macroglobulin synthesis in rat hepatocyte primary cultures

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Publication date
14 October 1985
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Published by Elsevier B.V.
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    Abstract

    AbstractIn rat hepatocyte primary cultures recombinant interleukin 1 was found to stimulate α2-macroglobulin synthesis, whereas albumin synthesis was decreased. Although recent experiments gave evidence that a hepato-cyte-stimulating factor distinct from interleukin 1 must exist, we conclude that interleukin 1 exerts a direct effect on hepatocytes by inducing acute-phase protein synthesis.Interleukin 1α2-MacroglobulinRat hepatocyt

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