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oaidoi:10.1016/j.ccr.2008.06.012

Deregulating EMT and Senescence: Double Impact by a Single Twist

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Publication date
8 July 2008
Publisher
Elsevier Inc.
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    Abstract

    The acquisition of a fully malignant phenotype is limited by several barriers, including cellular senescence and the requirement to undergo an epithelial-mesenchymal transition (EMT). Deregulation of these processes is believed to occur by largely independent events. In this issue of Cancer Cell, Ansieau et al. (2008) challenge this view

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