journal articlereview
oaidoi:10.1016/j.cell.2015.06.008

Wnt Down, Tumors Wind Up?

Authors
Publication date
18 June 2015
Publisher
Elsevier Inc.
Doi

    Abstract

    In mouse intestinal tumors induced by the inhibition of APC, the restoration of APC function causes complete tumor regression with normal differentiation and return of stem cell function irrespective of whether tumors also carried mutations in Kras and p53. These findings by Dow et al. validate the Wnt pathway as an exquisite target for intervention

    Similar works

    Full text

    thumbnail-image

    Elsevier - Publisher Connector

    redirect
    oaidoi:10.1016/j.cell.2015.06.008
    Last time updated on 05/05/2017

    This paper was published in Elsevier - Publisher Connector .

    Having an issue?

    Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.