Abolishment of inhibitory effects of 3'-deazaadenosine on Superoxide generation of guinea pig phagocytes by pre-exposure to phorbol myristate acetate

Yagawa, Katsuro; Nakanishi, Masayuki; Hayashi, Shinichiro; Kaku, Mariko; Ichinose, Yukito; Itoh, Tokuo; Tomoda, Akio; Yoneyama, Yoshimasa; Shigematsu, Nobuaki

journal article

Abolishment of inhibitory effects of 3'-deazaadenosine on Superoxide generation of guinea pig phagocytes by pre-exposure to phorbol myristate acetate

Authors: Katsuro Yagawa
Masayuki Nakanishi
Shinichiro Hayashi
Mariko Kaku
Yukito Ichinose
Tokuo Itoh
Akio Tomoda
Yoshimasa Yoneyama
Nobuaki Shigematsu
Publication date: 9 June 1986
Publisher: Published by Elsevier B.V.
Doi

Abstract

AbstractSuperoxide generation by guinea pig macrophages and polymorphonuclear leukocytes induced by wheat germ agglutinin, immune complexes or formyl-methionyl-leucyl-phenylalanine was inhibited considerably by 3'-deazaadenosine. The pre-exposure of the 3'-dezazaadenosine-treated cells to a small amount of phorbol myristate acetate abolished the inhibitory effect of 3'-deazaadenosine on the generation of Superoxide.Superoxide generation3'-DeazaadenosinePhorbol myristate acetateWheat germ agglutininImmune complexPhagocyt

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Elsevier - Publisher Connector

doi:10.1016/0014-5793(86)80625...

Last time updated on 04/05/2017

This paper was published in Elsevier - Publisher Connector .

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