journal articlereview
oaidoi:10.1016/j.cmet.2014.06.012

Mitochondrial Replacement Therapies Can Circumvent mtDNA-Based Disease Transmission

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Publication date
1 July 2014
Publisher
Elsevier Inc.
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    Abstract

    Mitochondrial DNA diseases are relatively common, sometimes devastating, and transmitted exclusively through the egg to children of carrier mothers. A study in Cell by Wang et al. (2014) adds the exciting possibility of a new therapy for preventing mitochondrial disease transmission predicated on the use of polar body genomes in mice

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