Short daily hemodialysis rapidly improves nutritional status in hemodialysis patients

Abstract

Short daily hemodialysis rapidly improves nutritional status in hemodialysis patients.BackgroundMalnutrition is a common problem in maintenance hemodialysis patients and is associated with increased mortality and morbidity. Interventions such as oral or intravenous nutritional supplements have often failed to improve nutritional status. We studied the effect of a daily dialysis program on nutritional parameters.MethodsEight patients treated with standard hemodialysis (SHD) 4 to 5 hours three times per week were converted to daily hemodialysis (DHD) 2 to 2.5 hours six times per week. Serum albumin, prealbumin, and total cholesterol were evaluated every three months. Anthropometry and dietary evaluation were performed every six months.ResultsSerum albumin rose from 39.0 ± 2.6 to 42.0 ± 3.1 and 43.0 ± 2.6 g/L, prealbumin from 0.36 ± 0.04 to 0.41 ± 0.05 and 0.42 ± 0.1 g/L, total cholesterol from 1.7 ± 0.4 to 1.9 ± 0.4 and 1.8 ±0.3 g/L at baseline and at 6 and 12 months, respectively, after switching patients to DHD. Daily protein intake increased from 1.29 ± 0.20 g/kg/day to 1.48 ± 0.60 and 1.90 ± 0.70 (P < 0.05). These changes were accompanied by a dry body weight increase of 2.4 ± 1.6kg (P < 0.005) at month 6 and 4.2 ± 2.8kg at one year (P < 0.05). Lean body mass increased from 47.7 ± 4.9kg to 49.1 ± 5.9 (P < 0.05) and 50.5 ± 6.2 (P < 0.05).ConclusionsDaily hemodialysis appears to be a suitable method to improve nutritional status in maintenance dialysis patients