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T-Cell Promiscuity in Autoimmune Diabetes

By Li Li, Bo Wang, Jeffrey A. Frelinger and Roland Tisch

Abstract

OBJECTIVE—It is well established that the primary mediators of β-cell destruction in type 1 diabetes are T-cells. Nevertheless, the molecular basis for recognition of β-cell–specific epitopes by pathogenic T-cells remains ill defined; we seek to further explore this issue

Topics: Immunology and Transplantation
Publisher: American Diabetes Association
OAI identifier: oai:pubmedcentral.nih.gov:2494676
Provided by: PubMed Central
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