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The Impact of Prevention on Reducing the Burden of Cardiovascular Disease

By Richard Kahn, Rose Marie Robertson, Robert Smith and David Eddy


OBJECTIVE—Cardiovascular disease (CVD) is prevalent and expensive. While many interventions are recommended to prevent CVD, the potential effects of a comprehensive set of prevention activities on CVD morbidity, mortality, and costs have never been evaluated. We therefore determined the effects of 11 nationally recommended prevention activities on CVD-related morbidity, mortality, and costs in the U.S

Topics: Reviews/Commentaries/ADA Statements
Publisher: American Diabetes Association
OAI identifier: oai:pubmedcentral.nih.gov:2494659
Provided by: PubMed Central
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    1. (2003). American Diabetes Association: Economic costs of diabetes in the U.S. in 2002. Diabetes Care 26:917–932,
    2. (2004). Association Consensus Panel: Guidelines for computer modeling of diabetes and its complications. Diabetes Care 27:2262–2265,
    3. (2004). Association: Prevention or delay of type 2 diabetes (Position Statement).
    4. (2005). Clinical outcomes and cost-effectiveness of strategiesformanagingpeopleathighrisk for diabetes.
    5. (2004). CM: Diabetes care quality in the Veterans Affairs health care system and commercial managed care: the TRIAD study.
    6. (1996). Cost-effectiveness in health and medicine.
    7. (2006). Disease Control and Prevention: Addressing the Nation’s Leading Killers,
    8. (2006). Disease Control and Prevention. Diabetes: Disabling, Deadly, and on the Rise.
    9. (2002). DM: Reduction in the incidence of type 2 diabetes with lifestyle interventionormetformin.NEnglJMed346:393– 403,
    10. (2002). Eddy DM: Archimedes: a new model for simulating health care systems—the mathematical formulation.
    11. (2007). Eddy DM: Equations for the Archimedes model (Technical report online),
    12. (2001). Education Program: Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285:2486–2497,
    13. (1971). EW: Thirty year trends in cardiovascular risk factor levelsamongUSadultswithdiabetes:National Health and Nutrition Examination Surveys,
    14. (2008). FlottemeschTJ,GoodmanMJ,SolbergLI: Priorities among effective clinical preventiveservices:resultsofasystematicreview and analysis.
    15. (2008). for Health Statistics: National Health and Nutrition Examination Study (NHANES) 4 (Web site). Available from http://www.cdc.gov/nchs/ nhanes.htm.
    16. (2006). for Quality Assurance (NCQA): Personal communication. Unpublished data derived from the 90th performance level for health plans in the NCQAsystemortheaverageperformance level achieved by physicians successfully achieving ADA/NCQA Physician Recognition,
    17. (2006). Ghushchyan V: Preferencebased EQ-5D index scores for chronic conditionsintheUnitedStates.MedDecis Making 26:410–420,
    18. (2006). Gjessing HK: Smoking and deaths between 40 and 70 years of age in women and men. Ann Intern Med 144:381–389,
    19. (2006). Healthy lifestyle factors in the primary prevention of coronary heart disease among men. Circulation 114:160– 167,
    20. (2006). JL: A self-regulation program for maintenance of weight loss.
    21. (2007). King A: Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors amongoverweightpremenopausalwomen.
    22. (2008). KM: Improvements in diabetes processes of care and intermediate outcomes: United States, 1988–2002. Ann Intern Med 144:465–474,
    23. (2003). KrouseKM,MichenerTL:Primarycare:is there enough time for prevention?
    24. (2006). Mariotto A,MillerB,FeuerE:SEERCancerStatistics Review,
    25. (2006). MJ: Aspirin, statins, or both drugs for the primary prevention of coronary heart disease events in men: a cost-utility analysis. Ann Intern Med 144:326–336,
    26. Mokdad AH: Aspirin use among U.S. adults: behavioral risk factor surveillance system.
    27. (2002). MulrowC:Aspirinfortheprimaryprevention of cardiovascular events: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 136: 161–172,
    28. (2003). O: Multifactorial interventionandcardiovasculardiseasein patientswithtype2diabetes.NEnglJMed 348:383–393,
    29. (2003). PW: Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. JAMA 290:891–897,
    30. (2001). PygoveMP,PhillipsCT,AtkinsD,Teutch SM,MulrowCD,LohrKN:Screeningand treating adults for lipid disorders.
    31. RichardAJ,RotherJ,WilsonPW,REACH Registry Investigators: International prevalence,recognition,andtreatmentforcardiovascular risk factor in outpatients with atherothrombosis.
    32. (2003). Schlessinger L: Archimedes: a trial-validated model of diabetes. Diabetes Care 26:3093–3101,
    33. (2003). Schlessinger L: Validation of the Archimedes diabetes model. Diabetes Care 26:3102–3110,
    34. (2006). Taubert KA: AHA/ACC guidelines forsecondarypreventionforpatientswith coronary and other atherosclerotic vascular disease:
    35. (2003). The Diabetes Prevention Program Research Group: Costs associated with the primary prevention of type 2 diabetes mellitus in the diabetes prevention program. Diabetes Care 26:1–12,
    36. Thun MJ: Preventing cancer, cardiovascular disease and diabetes: a common agenda for the American Cancer Society, American Diabetes Association, and American Heart Association Circulation 109:3244–3255,
    37. Two decades of progress in preventing vascular disease.
    38. (2002). update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases: American Heart Association Science Advisory and Coordinating Committee. Circulation 106:388–391,
    39. (2001). UusitupaM:Preventionoftype2diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.
    40. (2000). WC: Primary prevention of coronary heart disease in women through diet and lifestyle.
    41. (2004). Wender RC: Cancer screening and the periodic health examination. Cancer 100:1553–1557,

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