Location of Repository

Streptococcus iniae M-Like Protein Contributes to Virulence in Fish and Is a Target for Live Attenuated Vaccine Development

By Jeffrey B. Locke, Ramy K. Aziz, Mike R. Vicknair, Victor Nizet and John T. Buchanan
Topics: Research Article
Publisher: Public Library of Science
OAI identifier: oai:pubmedcentral.nih.gov:2483786
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles



    1. (2004). A functional C5a anaphylatoxin receptor in a teleost species.
    2. (1996). A live (delta aroA) Aeromonas salmonicida vaccine for furunculosis preferentially stimulates T-cell responses relative to B-cell responses in rainbow trout (Oncorhynchus mykiss).
    3. (2006). A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues.
    4. (1997). An alternating least squares approach to inferring phylogenies from pairwise distances.
    5. (1966). An immunological relationship between the group. A Streptococcus and mammalian muscle.
    6. (2007). Analysis of the polysaccharide capsule of the systemic pathogen Streptococcus iniae and its implications in virulence.
    7. (1994). Antigenic diversity within a family of M proteins from group A streptococci: evidence for the role of frameshift and compensatory mutations.
    8. (1997). Attenuation, persistence, and vaccine potential of an Edwardsiella ictaluri purA mutant.
    9. (1996). C5a peptidase alters clearance and trafficking of group A streptococci by infected mice.
    10. (2003). Characterization of a bovine lactoferrin binding protein of Streptococcus uberis.
    11. (2003). Characterization of a white bass (Morone chrysops) embryonic cell line with epithelial features.
    12. (2006). Characterization of Streptococcus iniae isolated from ornamental cyprinid fishes and development of challenge models.
    13. (2004). Cloning, expression, cellular distribution, and role in chemotaxis of a C5a receptor in rainbow trout: the first identification of a C5a receptor in a nonmammalian species.
    14. (1994). CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
    15. (1997). Comparison of the sequences and functions of Streptococcus equi M-like proteins SeM and SzPSe.
    16. (2000). Complement system of bony and cartilaginous fish.
    17. (2007). Complete genome of acute rheumatic fever-associated serotype M5 Streptococcus pyogenes strain manfredo.
    18. (2001). Complete genome sequence of an M1 strain of Streptococcus pyogenes.
    19. (1990). Conservation of a hexapeptide sequence in the anchor region of surface proteins from gram-positive cocci.
    20. (1995). Construction of a series of pACYC-derived plasmid vectors.
    21. (1990). Coregulation of type 12 M protein and streptococcal C5a peptidase genes in group A streptococci: evidence for a virulence regulon controlled by the virR locus.
    22. (1962). Current knowledge of type-specific M antigens of group A streptococci.
    23. (2008). Current status of group A streptococcal vaccine development.
    24. (2002). Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass.
    25. (1988). Dissecting the catalytic triad of a serine protease.
    26. (2006). Domains required for transcriptional activation show conservation in the mga family of virulence gene regulators.
    27. (1985). Epitopes of streptococcal M proteins shared with cardiac myosin.
    28. (2005). Evolution of the Zebrafish Model: From Development to Immunity and Infectious Disease.
    29. (2002). Extension of the Lancefield classification for group A streptococci by addition of 22 new M protein gene sequence types from clinical isolates: emm103 to emm124.
    30. (1989). Fc-receptor and M-protein genes of group A streptococci are products of gene duplication.
    31. (1997). Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.
    32. (2000). Genetic organisation of the M protein region in human isolates of group C and G streptococci: two types of multigene regulator-like (mgrC) regions.
    33. (2005). Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial ‘‘pan-genome’’.
    34. (2002). Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks.
    35. (2005). Genome sequencing in microfabricated high-density picolitre reactors.
    36. (1988). Group B streptococci inhibit the chemotactic activity of the fifth component of complement.
    37. (2001). Horizontal gene transfer and host specificity of beta-haemolytic streptococci: the role of a putative composite transposon containing scpB and lmb.M o l
    38. (2008). Identification and molecular characterisation of a fibrinogen binding protein from Streptococcus iniae.
    39. (2002). Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease.
    40. (1997). Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse.
    41. (2002). Identification of novel adhesins from Group B streptococci by use of phage display reveals that C5a peptidase mediates fibronectin binding.
    42. (2002). Immunogenicity of a 26-valent group A streptococcal vaccine.
    43. (2004). Improved prediction of signal peptides:
    44. (1987). In vivo Streptococcus pyogenes C5a peptidase activity: analysis using transposon- and nitrosoguanidine-induced mutants.
    45. (1985). Inhibition of complement-mediated opsonization and phagocytosis of Streptococcus pyogenes by D fragments of fibrinogen and fibrin bound to cell surface M protein.
    46. (2001). Innate antimicrobial peptide protects the skin from invasive bacterial infection.
    47. (1997). Invasive infections due to a fish pathogen,
    48. (2003). Invasive Streptococcus iniae infections outside North America.
    49. (1992). Lipoteichoic acid and M protein: dual adhesins of group A streptococci.
    50. (1994). M protein and protein F act as important determinants of cell-specific tropism of Streptococcus pyogenes in skin tissue.
    51. (1972). M protein-associated adherence of Streptococcus pyogenes to epithelial surfaces: prerequisite for virulence.
    52. (2004). M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage.
    53. (2000). M-like proteins of Streptococcus dysgalactiae.
    54. (1996). M-related protein (Mrp) contributes to group A streptococcal resistance to phagocytosis by human granulocytes.
    55. (1985). Mechanism of action of the group A streptococcal C5a inactivator.
    56. (1991). Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systems.
    57. (2002). Optimization of fusion PCR for in vitro construction of gene knockout fragments.
    58. (1998). Potency testing of a live, genetically attenuated vaccine for salmonids.
    59. (2001). Prevalence of Streptococcus iniae in tilapia, hybrid striped bass, and channel catfish on commercial fish farms in the United States.
    60. (2004). Production of recombinant C5a from rainbow trout (Oncorhynchus mykiss): role in leucocyte chemotaxis and respiratory burst.
    61. (2004). Promotion of fibronectin independent invasion by C5a peptidase into epithelial cells in group A Streptococcus.
    62. (1997). Proteins M6 and F1 are required for efficient invasion of group A streptococci into cultured epithelial cells.
    63. (2006). Recent advances on the complement system of teleost fish.
    64. (1969). Rheumatic fever following streptococcal vaccination. Report of three cases.
    65. (1991). Rheumatogenic streptococci and autoimmunity.
    66. (1991). Role of M protein in adherence of group A streptococci.
    67. (1997). Role of putative virulence factors of Streptococcus pyogenes in mouse models of long-term throat colonization and pneumonia.
    68. (2000). Single-primer PCR procedure for rapid identification of transposon insertion sites.
    69. (1995). Specific Binding of the Activator Mga to Promoter Sequences of the emm and scpA Genes in the Group A Streptococcus.
    70. (2008). Strain-Associated Virulence Factors of Streptococcus iniae in Hybrid Striped Bass. Veterinary Microbiology In Press, Accepted Manuscript..
    71. (1992). Streptococcal C5a peptidase is a highly specific endopeptidase.
    72. (2006). Streptococcal M protein: a multipotent and powerful inducer of inflammation.
    73. (1981). Streptococcal M protein: alpha-helical coiled-coil structure and arrangement on the cell surface.
    74. (1977). Streptococcal M protein: an antiphagocytic molecule assembled on the cell wall.
    75. (1989). Streptococcal M protein: molecular design and biological behavior.
    76. (2007). Streptococcus iniae b-hemolysin streptolysin S is a virulence factor in fish infection.
    77. (2007). Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish.
    78. (2005). Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine development.
    79. (1976). Streptococcus iniae sp.nov., a beta-hemolytic streptococcus isolated from an Amazon freshwater dolphin, Inia geoffrensis.I n t lJ system Bacteriol.
    80. (2001). Streptococcus iniae virulence is associated with a distinct genetic profile.
    81. (2007). Streptococcus iniae: an aquatic pathogen of global veterinary significance and a challenging candidate for reliable vaccination.
    82. (2003). Streptococcus pyogenes expressing M and M-like surface proteins are phagocytosed but survive inside human neutrophils.
    83. (2002). Streptococcus-zebrafish model of bacterial pathogenesis.
    84. (1991). Surfacedisorganized, attenuated mutants of Aeromonas salmonicida as furunculosis live vaccines.
    85. (2004). The auxotrophic aroA mutant of Aeromonas hydrophila as a live attenuated vaccine against A. salmonicida infections in rainbow trout (Oncorhynchus mykiss).
    86. (1998). The Biology Workbench–a seamless database and analysis environment for the biologist.
    87. (1981). The complement system in rainbow trout (Salmo gairdneri). II. Purification and characterization of the fifth component (C5).
    88. (2002). The group B streptococcal C5a peptidase is both a specific protease and an invasin.
    89. (2001). The InterPro database, an integrated documentation resource for protein families, domains and functional sites.
    90. (2007). The Mga virulence regulon: infection where the grass is greener.
    91. (2007). The National Microbial Pathogen Database Resource (NMPDR): a genomics platform based on subsystem annotation.
    92. (2008). The Pfam protein families database.
    93. (2008). The RAST Server: Rapid Annotations using Subsystems Technology.
    94. (2000). The serotype of type Ia and III group B streptococci is determined by the polymerase gene within the polycistronic capsule operon.
    95. (2005). The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes.
    96. (2007). Transcytosis of Streptococcus iniae through skin epithelial barriers: an in vitro study.
    97. (2003). Trojan horse effect: phagocyte-mediated Streptococcus iniae infection of fish.
    98. (2005). Use of Arthrobacter davidanieli as a live vaccine against Renibacterium salmoninarum and Piscirickettsia salmonis in salmonids.
    99. (1996). Using CLUSTAL for multiple sequence alignments.

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.