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Diagnostic immunofluorescence*

By William B. Cherry and Charles B. Reimer

Abstract

The standardization of diagnostic immunofluorescence is a complex problem because diagnostic results are greatly influenced by interacting factors, such as the equipment, materials, and techniques for expressing and recording fluorescence. Furthermore, the characteristics of immunofluorescence reagents depend on how they are manufactured and used. The adoption of stable reference preparations of such reagents appears to be the only practicable way of standardizing laboratory test results. Several professional and regulatory organizations are actively promoting this objective. Consensus evaluation may be the best method of introducing proposed standards. Basic and applied research must provide the information needed to improve reagents and tests

Topics: Standardization of Diagnostic Materials
OAI identifier: oai:pubmedcentral.nih.gov:2483064
Provided by: PubMed Central
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