journal articlereview
oaidoi:10.1016/j.devcel.2014.05.017

LINE-1 of Evidence for Fetal Oocyte Attrition by Retrotransposon

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Publication date
9 June 2014
Publisher
Elsevier Inc.
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    Abstract

    Fetal oocytes in mammals undergo extensive apoptosis during development. In this issue of Developmental Cell, Malki et al. (2014) provide insight into how and why such massive oocyte loss occurs through the demonstration that the expression level of LINE-1 retrotransposon defines the survival threshold and thus viability of fetal oocytes

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