journal articlereview
oaidoi:10.1016/j.str.2003.12.008

Induced Fit, Drug Design, and dUTPase

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Publication date
16 March 2004
Publisher
Cell Press. Published by Elsevier Ltd.
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    Abstract

    AbstractIn this issue of Structure, the crystal structure of trypanosomal dUTPase exemplifies convergent evolution and the role of induced fit in substrate recognition. This structure opens the door for developing antiparasitic therapies that induce cell death by targeting a dUTPase

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