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Transitioning Toward Evidence-Based Research in the Health Sciences for the XXI Century

By Francesco Chiappelli and Olivia S. Cajulis


This article discusses some of the misconceptions of evidence-based research in the health sciences. It proposes that since not all treatments in medicine and dentistry can be evidence-based, clinical applications of the evidence-based process should become a specialty. The case is particularly evident in dentistry. Therefore dentistry is taken in this article as a model for discussion. We propose that to approach dentistry from the viewpoint of the patient-oriented evidence that matters (POEM) is perfectly acceptable so far as we also engage in the process of research evaluation and appraisal in dentistry (READ). We distinguish between dentistry based on the evidence, and evidence-based dentistry. We argue that when invoking an evidence-based approach to dentistry or medicine, it is not sufficient to establish the ‘levels of evidence’, but rather that all evidence-based clinical intervention must undergo the stringent process of evidence-based research so that clinical practice guidelines be revised based on the best available evidence

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Publisher: Oxford University Press
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Provided by: PubMed Central
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    1. (1997). A guide to interpreting discordant systematic reviews.
    2. Antibiotic prophylaxis: The evidence base for the efficacy of antibiotic prophylaxis in dental practice.
    3. (1994). Decision Analysis and Cost-Effectiveness Analysis: Methods for Quantitative Synthesis in Medicine.
    4. (2003). Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Qual Saf Health Care
    5. (2007). et al (eds).
    6. (2003). Evidence-Based Dentistry and Translational Research. J Evid Based Dent Pract
    7. Evidence-based dentistry in clinical practice.
    8. (1998). Evidence-based dentistry: what is it, and what does it have to do with practice? Quintessence Int
    9. Evidence-based medicine: what it is and What it isn’t.
    10. (2006). Evidence-based research in complementary and alternative medicine II: the process of evidence-based research. Evid Based Complement Alternat Med
    11. (2006). Evidence-based research in complementary and alternative medicine III: treatment of patients with Alzheimer’s disease. Evid Based Complement Alternat Med
    12. (2006). Implementing evidence-based decision making in the private practice setting: The 4-step process. J Evid Based Dent Pract
    13. Short blocks from the noncoding parts of the human genome have instances within nearly all known genes and relate to biological processes,
    14. (2007). Suppression of microRNA-silencing pathway by HIV-1 during virus replication.
    15. (2001). Systematic reviews of evaluations of diagnostic and screening tests. In: Egger
    16. The clinical expert: an empiric oddity.
    17. The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials.
    18. (2006). The importance of teaching critical thinking early in dental education: Concept, flow and history of the NYU 4-year curriculum or ‘‘miracle on 24th Street: The EBD version’’. J Evid Based Pract
    19. (2005). The molecular immunology of mucositis: implications for evidence-based research in alternative and complementary palliativetreatments. Evid Based Complement Alternat Med
    20. (1997). The relation between systematic research and practice guidelines. Academia and Clinic
    21. (2007). The Science of Research Synthesis:
    22. (2004). Tools and methods for evidence-based research in dental practice: preparing the future. 1st int conf evidence-based dental practice, proceedings. J Evid Based Dent Pract

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