Location of Repository

The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis

By N Kamesh, Gopala K Aradhyam and Narayanan Manoj
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:2396169
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles



    1. (1985). A case of lethal congenital dwarfism with accelerated skeletal maturation. Pediatr Radiol
    2. (1999). A novel parathyroid hormone (PTH)/ PTH-related peptide receptor mutation in Jansen's metaphyseal chondrodysplasia.
    3. (1998). Amizuka N: Inactivating mutation in the human parathyroid hormone receptor type 1 gene in Blomstrand chondrodysplasia. Endocrinology
    4. (2006). Application of phylogenetic networks in evolutionary studies. Mol Biol Evol
    5. (2001). Apweiler R: InterProScan – an integration platform for the signature-recognition methods in InterPro. Bioinformatics
    6. (1993). AR: CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum. Genes Dev
    7. (1995). CE: A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Nat Genet
    8. (2006). Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.
    9. (1996). Constitutively activated receptors for parathyroid hormone and parathyroid hormone-related peptide in Jansen's metaphyseal chondrodysplasia.
    10. (1993). Correction: LDL receptorrelated protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation. Cell
    11. (2005). Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors.
    12. (1993). Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature
    13. (1988). Devreotes PN: A chemoattractant receptor controls development in Dictyostelium discoideum. Science
    14. (1993). Devreotes PN: Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development. Genes Dev
    15. (2005). Di Gregorio A: Ciona intestinalis: chordate development made simple. Dev Dyn
    16. (2006). DJ: Defining the origins and evolution of the chemokine/chemokine receptor system.
    17. (2000). DL: The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in Frizzled receptors mediates Wnt/beta-catenin signalling.
    18. (2000). Drug discovery: a historical perspective. Science
    19. (1988). DW: Mutational analysis of the ligand binding domain of the low density lipoprotein receptor.
    20. (1984). DW: The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell
    21. (1985). DW: The LDL receptor gene: a mosaic of exons shared with different proteins. Science
    22. (1994). E: A G protein-coupled receptor with low density lipoprotein-binding motifs suggests a role for lipoproteins in G-linked signal transduction.
    23. Elements of Chordate Anatomy
    24. (1998). Evidence for a ligand interaction site at the amino-terminus of the parathyroid hormone (PTH)/PTH-related protein receptor from cross-linking and mutational studies.
    25. (1998). Extended life-span and stress resistance in the Drosophila mutant methuselah. Science
    26. (1996). FE: An evolutionary trace method defines binding surfaces common to protein families.
    27. (2006). Fredriksson R: The G protein-coupled receptor subset of the chicken genome. PLoS Comput Biol
    28. (2005). Fredriksson R: The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish. Mol Phylogenet Evol
    29. (2000). G: EDG receptors as a therapeutic target in the nervous system.
    30. (2002). Gene expression profiles in tadpole larvae of Ciona intestinalis. Dev Biol
    31. (1985). Genes-in-pieces revisited. Science
    32. (1997). GG: Molecular approaches to receptors as targets for drug discovery.
    33. (2001). Godzik A: Clustering of highly homologous sequences to reduce the size of large protein databases. Bioinformatics
    34. (2002). Grimmelikhuijzen CJ: Molecular identification of the insect adipokinetic hormone receptors. Proc Natl Acad Sci USA
    35. (1995). H: A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science
    36. (2004). Hadwiger JA: A cAMP receptor-like G protein-coupled receptor with roles in growth regulation and development. Dev Biol
    37. (2006). Hallbook F: Three insulinrelaxin-like genes in Ciona intestinalis. Peptides
    38. (2007). HB: The Adhesion GPCRs: a unique family of G protein-coupled receptors with important roles in both central and peripheral tissues. Cell Mol Life Sci
    39. (2007). HB: The G protein-coupled receptor subset of the rat genome.
    40. (1988). High density lipoproteins stimulate placental lactogen release and adenosine 3',5'-monophosphate (cAMP) production in human trophoblast cells: evidence for cAMP as a second messenger in human placental lactogen release. Endocrinology
    41. (2001). I: The HMMTOP transmembrane topology prediction server. Bioinformatics
    42. (2007). Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets. Biochim Biophys Acta
    43. (2003). JD: Multiple sequence alignment with the Clustal series of programs.
    44. (1989). JL: Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins.
    45. (1990). Lipman DJ: Basic local alignment search tool.
    46. (1997). Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res
    47. (2001). Little PF: The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. Mech Dev
    48. (1990). Low-density lipoprotein elevates intracellular calcium and pH in vascular smooth muscle cells and fibroblasts without mediation of LDL receptor.
    49. (2000). Mapping the bimolecular interface of the parathyroid hormone (PTH)-PTH1 receptor complex: spatial proximity between Lys(27) (of the hormone principal binding domain) and leu(261) (of the first extracellular loop) of the human PTH1 receptor. Biochemistry
    50. (2005). Miczek KA: Glutamate receptor subtypes: promising new pharmacotherapeutic targets. Psychopharmacology (Berl)
    51. (2007). Mierke DF: Structural features of parathyroid hormone receptor coupled to Galpha(s)-protein. Biophys J
    52. (2007). Mining the gene repertoire and ESTs for G protein-coupled receptors with evolutionary perspective. Acta Physiol (Oxf)
    53. (1999). Modelling G-protein-coupled receptors for drug design. Biochim Biophys Acta
    54. (2005). NM: Tunicate gonadotropin-releasing hormone (GnRH) peptides selectively activate Ciona intestinalis GnRH receptors and the green monkey type II GnRH receptor. Endocrinology
    55. (1994). Nussbaum SR, Kronenberg HM: Determinants of [Arg2]PTH-(1–34) binding and signaling in the transmembrane region of the parathyroid hormone receptor. Endocrinology
    56. (2006). P: SMART 5: domains in the context of genomes and networks.
    57. (1998). Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies.
    58. (1989). PHYLIP – Phylogeny Inference Package (Version3.2). Cladistics
    59. (2003). Phylogeny for the faint of heart: a tutorial. Trends Genet
    60. (2003). PipeAlign: A new toolkit for protein family analysis. Nucleic Acids Res
    61. Pletscher A: Low density lipoprotein causes general cellular activation with increased phosphatidylinositol turnover and lipoprotein catabolism.
    62. (1989). PN: A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains. Nature
    63. (1998). Profile hidden Markov models. Bioinformatics
    64. (2004). PS: The Frizzled family: receptors for multiple signal transduction pathways. Genome Biol
    65. (1992). Purified alpha 2-macroglobulin receptor/LDL receptorrelated protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes.
    66. (2003). RE: PTHrP, PTHr, and FGFR3 are involved in the process of endochondral ossification in human osteophytes. Histochem Cell Biol
    67. (2004). Satoh N: Tachykinin and tachykinin receptor of an ascidian, Ciona intestinalis: evolutionary origin of the vertebrate tachykinin family.
    68. (2006). Schioth HB: Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse. Genomics
    69. (2003). Schioth HB: The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol
    70. (2005). Schioth HB: The repertoire of G-protein-coupled receptors in fully sequenced genomes. Mol Pharmacol
    71. (1997). Segre GV: Mutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTHrelated protein receptor result in selective loss of PTH-stimulated phospholipase C activity.
    72. (1996). Shoback DM: The N-terminal region of the third intracellular loop of the parathyroid hormone (PTH)/PTH-related peptide receptor is critical for coupling to cAMP and inositol phosphate/Ca2+ signal transduction pathways.
    73. (2008). Silve C: A homozygous inactivating mutation in the parathyroid hormone/parathyroidBMC Evolutionary Biology
    74. (2001). Sonnhammer EL: Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
    75. (1998). SOSUI: classification and secondary structure prediction system for membrane proteins. Bioinformatics
    76. (2005). Sowdhamini R: Genome wide survey of G proteincoupled receptors in Tetraodon nigroviridis.
    77. (2001). Sphingosine-1-phosphate: an emerging therapeutic target. Expert Opin Ther Targets
    78. (2005). Summers RJ: Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8). J Pharmacol Exp Ther
    79. (1988). Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.
    80. (1998). Suva LJ: Arginine 186 in the extracellular N-terminal region of the human parathyroid hormone 1 receptor is essential for contact with position 13 of the hormone. Mol Endocrinol
    81. (2005). T: MAFFT version 5: improvement in accuracy of multiple sequence alignment. Nucleic Acids Res
    82. (2006). The 7 TM G-protein-coupled receptor target family. ChemMedChem
    83. (2008). The Branchiostoma genome contains a highly diversified set of G protein-coupled receptors.
    84. (2006). The Dictyostelium repertoire of seven transmembrane domain receptors.
    85. (2002). The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science
    86. (2003). The first tunicate from the Early Cambrian of South China. Proc Natl Acad Sci USA
    87. (1970). The Vertebrate Body 4th edition.
    88. (1995). TJ: Homolog-scanning mutagenesis of the parathyroid hormone (PTH) receptor reveals PTH-(1–34) binding determinants in the third extracellular loop. Mol Endocrinol
    89. (2003). TJ: Identification of a contact site for residue 19 of parathyroid hormone (PTH) and PTH-related protein analogs in transmembrane domain two of the type 1 PTH receptor. Mol Endocrinol
    90. (1999). TJ: Receptors for PTH and PTHrP: their biological importance and functional properties.
    91. (1997). TJ: Residues in the membrane-spanning and extracellular loop regions of the parathyroid hormone (PTH)-2 receptor determine signaling selectivity for PTH and PTH-related peptide.
    92. (1999). TJ: The hydrophobic residues phenylalanine 184 and leucine 187 in the type-1 parathyroid hormone (PTH) receptor functionally interact with the amino-terminal portion of PTH-(1–34).
    93. (1996). Transmembrane residues of the parathyroid hormone (PTH)/PTH-related peptide receptor that specifically affect binding and signaling by agonist ligands.
    94. (1998). Transmembrane residues together with the amino terminus limit the response of the parathyroid hormone (PTH) 2 receptor to PTH-related peptide.
    95. (1996). TreeView: an application to display phylogenetic trees on personal computers.
    96. (2003). Tregear GW: Relaxin: new peptides, receptors and novel actions. Trends Endocrinol Metab
    97. (2006). Tunicates and not cephalochordates are the closest living relatives of vertebrates. Nature
    98. (1999). Ushikubi F: Prostanoid receptors: structures, properties, and functions. Physiol Rev
    99. (1999). Ushkaryov Y: The latrophilin family: multiply spliced G protein-coupled receptors with differential tissue distribution. FEBS Lett
    100. (2002). von Haeseler A: TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing. Bioinformatics
    101. (2003). Vriend G: GPCRDB information system for G protein-coupled receptors. Nucleic Acids Res
    102. (1978). Why genes in pieces? Nature
    103. (2002). Zwiebel LJ: G protein-coupled receptors in Anopheles gambiae. Science

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.